Surface Functionalization by Strain-Promoted Alkyne-Azide Click Reactions

Clicks without Cu: There is a growing demand for reproducible site‐specific functionalization of surfaces with biomolecules without introduction of unwanted groups or catalysts, as they may interfere with later applications. The title reactions (see picture) could fulfill these requirements, and fou...

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Bibliographic Details
Published inAngewandte Chemie (International ed.) Vol. 50; no. 24; pp. 5428 - 5430
Main Authors Manova, Radostina, van Beek, Teris A., Zuilhof, Han
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 06.06.2011
WILEY‐VCH Verlag
Wiley Subscription Services, Inc
EditionInternational ed. in English
Subjects
alkynes
azides
chemistry
click chemistry
immobilization
surface chemistry
surface functionalization
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Summary:Clicks without Cu: There is a growing demand for reproducible site‐specific functionalization of surfaces with biomolecules without introduction of unwanted groups or catalysts, as they may interfere with later applications. The title reactions (see picture) could fulfill these requirements, and four recent applications are discussed.
Bibliography:EU
Dutch Ministry of Economic Affairs, Province of Gelderland
Euregio Rhein-Waal
istex:B54E02066945A33D3AB82F715B0DD7143A7C9B2B
This work is co-financed by the INTERREG IV, a Germany-Netherlands program, through EU funding from the European Regional Development Fund, the MWEBWV of North-Rhine Westphalia, the Dutch Ministry of Economic Affairs, Province of Gelderland, and the program management Euregio Rhein-Waal.
MWEBWV of North-Rhine Westphalia
ArticleID:ANIE201100835
ark:/67375/WNG-0MZLJC5K-B
This work is co‐financed by the INTERREG IV, a Germany–Netherlands program, through EU funding from the European Regional Development Fund, the MWEBWV of North‐Rhine Westphalia, the Dutch Ministry of Economic Affairs, Province of Gelderland, and the program management Euregio Rhein‐Waal.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201100835