Exosomal communication goes viral

• Published in: Journal of virology Vol. 89; no. 10; pp. 5200 - 5203
• Main Author: Meckes, Jr, David G
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.05.2015
• Subjects: Cell Communication - physiology; Epstein-Barr virus; Epstein-Barr Virus Infections - immunology; Epstein-Barr Virus Infections - physiopathology; Epstein-Barr Virus Infections - virology; Exosomes - physiology; Exosomes - virology; Gems; Herpesvirus 4, Human - immunology; Herpesvirus 4, Human - pathogenicity; Herpesvirus 4, Human - physiology; Host-Pathogen Interactions; Humans; Immune Evasion; Models, Biological; Viral Matrix Proteins - physiology

Exosomes are small vesicles secreted from cells that participate in intercellular communication events. Accumulating evidence demonstrates that host exosome pathways are hijacked by viruses and that virally modified exosomes contribute to virus spread and immune evasion. In the case of tumor viruses...