The benefits of higher LMR for early threatened abortion: A retrospective cohort study

• Published in: PloS one Vol. 15; no. 4; p. e0231642
• Main Authors: Feng, Qiu-Ting, Chen, Chi, Yu, Qing-Ying, Chen, Si-Yun, Huang, Xian, Zhong, Yan-Lan, Luo, Song-Ping, Gao, Jie
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 20.04.2020; Public Library of Science (PLoS)
• Subjects: Abortion; Biology and Life Sciences; Blood; Chi-square test; Chinese medicine; Cohort analysis; Hospitals; Inflammation; Lymphocytes; Medical prognosis; Medicine and Health Sciences; Miscarriage; Pregnancy; Regression analysis; Regression models; Statistical analysis; Statistical tests; Studies; Traditional Chinese medicine; Variables; Womens health; China
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0231642

To investigate the relation of inflammation-related parameters and pregnancy outcome in women with the early threatened abortion. 630 women with early threatened abortion were divided into two groups based on the pregnancy outcome. All of them had the blood routine examination before treating. The differences between two groups were analyzed by the Chi-squared test, Student T test, Mann-Whitney U test, Binary Logistic Regression, Marginal Structural Model and Threshold effect analysis. We found that there is no significant difference in the pregnancy outcome for NLR (OR:0.92, CI95%:0.72, 1.17) and PLR (OR:1.00, CI%:0.99, 1.01). However, a difference had a statistical significance in the pregnancy outcome when LMR less than 2.19 (OR:0.39, CI95%:0.19,0.82). This study suggested that higher LMR was related to the lower risk of miscarriage in the women with early threatened abortion in a way.