Solitary Fibrous Tumor with Rapid Progression after 16 Years' Follow Up

• Published in: Internal Medicine Vol. 53; no. 6; pp. 617 - 621
• Main Authors: Okimoto, Tamio, Horimasu, Yasushi, Hamaguchi, Shunichi, Sutani, Akihisa, Amano, Chika, Harada, Yuji, Maruyama, Riruke, Miyamoto, Nobuhiro, Kishimoto, Koji, Isobe, Takeshi
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01.01.2014
• Subjects: Aged; Biopsy, Fine-Needle - methods; Disease Progression; Dyspnea - etiology; Fatal Outcome; Fatigue - etiology; Female; Follow-Up Studies; Humans; malignant solitary fibrous tumor; Solitary Fibrous Tumor, Pleural - complications; Solitary Fibrous Tumor, Pleural - diagnosis; Solitary Fibrous Tumor, Pleural - pathology; Time Factors; transformation
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.53.1657

A 79-year-old woman was admitted to our hospital for an investigation of a large 13-cm tumor in the chest and treatment for dyspnea in January 2010. The tumor had been observed on chest X-rays since 1992. It had measured 7 cm in 2008, then started to grow rapidly. Further investigations revealed that it was a malignant solitary fibrous tumor that was strongly suspected to have transformed from a benign to malignant state. Resection was not possible, and the patient died one month later. Benign solitary fibrous tumors of the pleura may become malignant during long-term follow-up. All suspected or proven solitary fibrous tumors of the pleura should be resected.