A 27-Year-Old Woman Diagnosed as Polycystic Ovary Syndrome Associated with Graves' Disease

• Published in: Internal Medicine Vol. 50; no. 19; pp. 2185 - 2189
• Main Authors: Jung, Jung Hwa, Hahm, Jong Ryeal, Jung, Tae Sik, Kim, Hee Jin, Kim, Ho Soo, Kim, Sungsu, Kim, Soo Kyoung, Lee, Sang Min, Kim, Deok Ryong, Choi, Won Jun, Seo, Yeong Mi, Chung, Soon Il
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01.01.2011
• Subjects: Female; Graves Disease - complications; Graves Disease - diagnosis; Graves Disease - drug therapy; Graves' disease; Humans; Insulin Resistance; Oligomenorrhea - etiology; polycystic ovary syndrome; Polycystic Ovary Syndrome - complications; Polycystic Ovary Syndrome - diagnosis; Thinness - complications; Young Adult
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.50.5475

Polycystic ovary syndrome (PCOS) and Graves' disease are the common causes of menstrual irregularity leading to infertility in women of child-bearing age. A 21-year-old female patient visited us with complaints of oligomenorrhea and hand tremor. She was diagnosed as having PCOS and hyperthyroid Graves' disease, simultaneously. She had low body weight (BMI: 16.4 kg/m2), mild hirsutism, and thyrotoxicosis. The patient was treated with anti-thyroid drug and beta-blocker for about two years, and then recovered to normal thyroid function. Although some studies have suggested a connection between PCOS and autoimmune thyroiditis, no study indicated that PCOS is associated with Graves' disease until now. Here, we describe the first case report of a lean woman with normal insulin sensitivity presenting PCOS and Graves' disease simultaneously.