Eosinophilic Fasciitis Complicated with Peripheral Polyneuropathy

• Published in: Internal Medicine Vol. 37; no. 4; pp. 417 - 420
• Main Authors: MORIGUCHI, Masato, TERAI, Chihiro, KUROKI, Soemu, TANAKA, Eiichi, SOMEYA, Noriyuki, TSUNODA, Yoshiho, KASHIWAZAKI, Sadao
• Format: Journal Article
• Language: English
• Published: Tokyo The Japanese Society of Internal Medicine 1998; Japanese Society of Internal Medicine
• Subjects: Adult; Biological and medical sciences; Biopsy; Eosinophilia - complications; Eosinophilia - diagnosis; Eosinophilia - drug therapy; eosinophilia-myalgia syndrome; Fascia - pathology; Fasciitis - complications; Fasciitis - diagnosis; Fasciitis - drug therapy; Female; Follow-Up Studies; Glucocorticoids - therapeutic use; Humans; hypereosinophilic syndrome; Magnetic Resonance Imaging; major basic protein; Medical sciences; mononeuritis multiplex; Neural Conduction; Peripheral Nervous System Diseases - drug therapy; Peripheral Nervous System Diseases - etiology; Peripheral Nervous System Diseases - physiopathology; polyneuropathy; Prednisolone - therapeutic use; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Human; Connective tissue disease; Skin disease; Nervous system diseases; Polyneuropathy; Eosinophilia; Fasciitis; Case study; Systemic disease; Complication; Peripheral nerve disease; Diagnosis; Hypereosinophilic syndrome
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.37.417

Peripheral polyneuropathy and the complication of eosinophilic fasciitis (EF) is rare; only 2 such cases have been described previously. A 40-year-old woman suffered from swelling of the extremities after strenuous exercise and complained of bilateral paresthesia on the soles of her feet. The diagnosis was EF according to clinical symptoms, peripheral eosinophilia, and histological examination of the fascia. Nerve conduction tests also revealed sensory disturbance as mononeuritis multiplex. After administration of prednisolone, the swelling and tenderness of the extremities improved immediately but the neuropathy lasted for 6 months. (Internal Medicine 37: 417-420, 1998)