Transient aplastic crisis in a leukemic child caused by parvovirus B19 infection

Acute parvovirus B19 infection was confirmed in an 8-year-old girl with acute lymphoblastic leukemia on maintenance therapy by electron microscopy, DNA, and serological techniques. Clinical manifestations were typical of severe anemia, fever, leukopenia, and thrombocytopenia. Increased levels of ser...

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Bibliographic Details
Published inPediatric hematology and oncology Vol. 13; no. 2; p. 173
Main Authors Mihál, V, Dusek, J, Hajdúch, M, Cohen, B J, Fingerová, H, Veselý, J
Format Journal Article
LanguageEnglish
Published England 1996
Subjects
Acute Disease
Anemia, Aplastic - etiology
Child
Erythema Infectiosum - complications
Female
Humans
Parvovirus B19, Human
Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications
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Summary:Acute parvovirus B19 infection was confirmed in an 8-year-old girl with acute lymphoblastic leukemia on maintenance therapy by electron microscopy, DNA, and serological techniques. Clinical manifestations were typical of severe anemia, fever, leukopenia, and thrombocytopenia. Increased levels of serum erythropoietin were detected in the course of the infection. The patient's recovery was supported by corticosteroids, red blood cell transfusions, G-CSF, and commercial immunoglobulin preparations.
ISSN:0888-0018
DOI:10.3109/08880019609030809