Angiosarcoma of the scalp associated with Xeroderma pigmentosum

Abstract Xeroderma pigmentosum (XP) is a rare autosomal recessive genodermatosis associated with hypersensitivity to ultraviolet light due to defects in Deoxyribonucleic acid (DNA) repair. These patients have more than a 1000-fold increased risk of developing skin cancers. Although multiple cutaneou...

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Bibliographic Details
Published inIndian journal of medical and paediatric oncology Vol. 33; no. 2; pp. 126 - 129
Main Authors Sharma, Shilpi, Deshmukh, Anuja D, Bal, Munita M, Chaukar, Devendra A, Dcruz, Anil K
Format Journal Article
LanguageEnglish
Published A-12, 2nd Floor, Sector 2, Noida-201301 UP, India Thieme Medical and Scientific Publishers Pvt. Ltd 01.04.2012
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Medknow Publications & Media Pvt Ltd
Subjects
Angiosarcoma
Care and treatment
CASE REPORT
Case studies
Diagnosis
Genetic aspects
Genetic disorders
Head
Radiotherapy
Skin diseases
Tumors
Xeroderma pigmentosum
Xeroderma pigmentosum
Angiosarcoma
genodermatosis
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Summary:Abstract Xeroderma pigmentosum (XP) is a rare autosomal recessive genodermatosis associated with hypersensitivity to ultraviolet light due to defects in Deoxyribonucleic acid (DNA) repair. These patients have more than a 1000-fold increased risk of developing skin cancers. Although multiple cutaneous malignancies are common, the simultaneous occurrence of angiosarcoma and basal cell carcinoma is a rare phenomenon. We report a case of a 25-year-old male with XP with angiosarcoma scalp and basal cell carcinoma of face and occiput and discuss the treatment of this aggressive neoplasm with a review of the literature pertaining to it.
ISSN:0971-5851
0975-2129
DOI:10.4103/0971-5851.99753