Insight into the dynamics, localization and magnitude of antigen-specific immune responses by [18F]FLT PET imaging

In order for cellular therapeutics to succeed, comprehensive monitoring of the transplanted cells in vivo is required i.e., their localization, functionality and numbers in a longitudinal manner. Recently, dendritic cell based vaccines have been monitored by their effect on lymphocyte activation usi...

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Published inOncoimmunology Vol. 1; no. 5; pp. 744 - 745
Main Authors Aarntzen, Erik H.J.G., Srinivas, Mangala, Punt, Cornelius J.A., Figdor, Carl G., Oyen, Wim J.G., de Vries, I. Jolanda M.
Format Journal Article
LanguageEnglish
Published United States Taylor & Francis 01.08.2012
Landes Bioscience
Subjects
Author's View
Binding
Biology
Bioscience
Calcium
Cancer
Cell
cell therapy
cell tracking
Cycle
dendritic cell-based vaccines
F]FLT-PET
immunomonitoring
Landes
Organogenesis
Proteins
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Summary:In order for cellular therapeutics to succeed, comprehensive monitoring of the transplanted cells in vivo is required i.e., their localization, functionality and numbers in a longitudinal manner. Recently, dendritic cell based vaccines have been monitored by their effect on lymphocyte activation using [ 18 F]FLT PET in cancer patients.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:2162-4011
2162-402X
2162-402X
DOI:10.4161/onci.19533