Case of uterine leiomyoma showing fludeoxyglucose uptake on F-18 fludeoxyglucose positron emission tomography/computed tomography

• Published in: The journal of obstetrics and gynaecology research Vol. 36; no. 6; pp. 1261 - 1264
• Main Authors: Park, Jee Hyun, Han, Jee Young, Hyun, In Young, Lee, Byoung Ick, Moon, Yeon Sook
• Format: Journal Article
• Language: English
• Published: Melbourne, Australia Blackwell Publishing Asia 01.12.2010
• Subjects: False Positive Reactions; Female; Fluorodeoxyglucose F18; Humans; Leiomyoma - diagnostic imaging; Middle Aged; positron emission tomography/computed tomography (PET/CT); Positron-Emission Tomography; Postmenopause; Radiopharmaceuticals; uterine leiomyoma; Uterine Neoplasms - diagnostic imaging
• ISSN: 1341-8076; 1447-0756
• DOI: 10.1111/j.1447-0756.2010.01307.x

In order not to over treat uterine leiomyoma and to avoid overlooking uterine leiomyosarcoma, a highly reliable diagnostic method has been thought. Occasionally, it is difficult to discriminate uterine leiomyoma from uterine leiomyosarcoma. Recently positron emission tomography/computed tomography (PET/CT) has been proved useful in assessing pelvic malignancies. We experienced a case of uterine leiomyoma showing increased F‐18 fludeoxyglucose uptake on PET/CT in a postmenopausal woman. However, histological analysis demonstrated benign leiomyoma by the hysterectomy. Immunohistochemical analysis of glucose transporter‐1 showed negative in leiomyoma. Our case indicates that uterine leiomyoma in a postmenopausal woman may show false positive result of PET/CT.