Enalapril induced severe hyponatremia and altered sensorium in a child

• Published in: Indian journal of pharmacology Vol. 43; no. 5; pp. 605 - 606
• Main Authors: Zaki, Syed Ahmed, Bhongade, Swapnil, Shanbag, Preeti
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.09.2011; Medknow Publications & Media Pvt. Ltd; Medknow Publications
• Subjects: ACE inhibitors; Case studies; Complications and side effects; Diagnosis; Dosage and administration; Drug therapy; Drug Watch; Enalapril; Enalaprilat; Hyponatremia; Patient outcomes; Pediatrics; Pharmacology; Risk factors; Side effects; India; Enalapril; syndrome of inappropriate antidiuretic hormone; renin angiotensin system; hyponatremia

Enalapril is an angiotensin converting enzyme inhibitor widely used in children for treatment of hypertension and congestive cardiac failure. We report a 5-year-old boy who developed severe hyponatremia and altered sensorium on enalapril therapy. The serum sodium gradually became normal within 3 day...