Enalapril induced severe hyponatremia and altered sensorium in a child

Enalapril is an angiotensin converting enzyme inhibitor widely used in children for treatment of hypertension and congestive cardiac failure. We report a 5-year-old boy who developed severe hyponatremia and altered sensorium on enalapril therapy. The serum sodium gradually became normal within 3 day...

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Bibliographic Details
Published inIndian journal of pharmacology Vol. 43; no. 5; pp. 605 - 606
Main Authors Zaki, Syed Ahmed, Bhongade, Swapnil, Shanbag, Preeti
Format Journal Article
LanguageEnglish
Published India Medknow Publications and Media Pvt. Ltd 01.09.2011
Medknow Publications & Media Pvt. Ltd
Medknow Publications
Subjects
ACE inhibitors
Case studies
Complications and side effects
Diagnosis
Dosage and administration
Drug therapy
Drug Watch
Enalapril
Enalaprilat
Hyponatremia
Patient outcomes
Pediatrics
Pharmacology
Risk factors
Side effects
India
Enalapril
syndrome of inappropriate antidiuretic hormone
renin angiotensin system
hyponatremia
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Summary:Enalapril is an angiotensin converting enzyme inhibitor widely used in children for treatment of hypertension and congestive cardiac failure. We report a 5-year-old boy who developed severe hyponatremia and altered sensorium on enalapril therapy. The serum sodium gradually became normal within 3 days. The patient's sensorium improved significantly on correction of hyponatremia. Through this case, we highlight the importance of monitoring serum sodium in patients on enalapril therapy.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0253-7613
1998-3751
DOI:10.4103/0253-7613.84984