Bone Mineral Density Screening and the Frequency of Osteopenia/Osteoporosis in Turkish Adult Patients With Celiac Disease

• Published in: The Turkish journal of gastroenterology Vol. 32; no. 7; pp. 600 - 607
• Main Authors: Sayar, Süleyman, Aykut, Hüseyin, Kaya, Özkan, Kürbüz, Kemal, Ak, Çağatay, Gökçen, Pınar, Mutlu Bilgiç, Nermin, Adalı, Gupse, Kahraman, Resul, Doganay, Levent, Özdil, Kâmil
• Format: Journal Article
• Language: English
• Published: Turkey AVES 01.07.2021; Turkish Society of Gastroenterology
• Subjects: Absorptiometry, Photon; Adult; Bone Density; Bone Diseases, Metabolic - diagnostic imaging; Bone Diseases, Metabolic - epidemiology; Bone Diseases, Metabolic - etiology; Bones; Celiac disease; Celiac Disease - complications; Celiac Disease - diet therapy; Celiac Disease - epidemiology; Complications and side effects; Density; Diagnosis; Diet, Gluten-Free; Female; Humans; LIVER; Male; Mass Screening; Middle Aged; Original; Osteopenia; Osteoporosis; Osteoporosis - diagnostic imaging; Osteoporosis - epidemiology; Osteoporosis - etiology; Prevalence; Retrospective Studies; Risk factors; Statistics; Turkey - epidemiology; Young Adult; Turkey
• ISSN: 1300-4948; 2148-5607
• DOI: 10.5152/tjg.2021.20313

The aim of this study was to evaluate the prevalence of osteopenia and osteoporosis in adult patients with celiac disease (CD) at diagnosis and/or in the follow-up after a gluten-free diet (GFD). Adult patients diagnosed with CD were retrospectively screened through follow-up records and computer databases. Patients assessed by dual-energy X-ray absorptiometry (DEXA) at diagnosis and/or in the follow-up after a GFD were included in the study. One hundred patients who underwent a DEXA scan at least once after diagnosis or after being on a GFD were included in the study. The mean age of the patients at diagnosis was 34.61 ± 10.3 years, and 84% of the patients (n = 84) were female. At the time of diagnosis (n = 46), the prevalence of osteopenia and osteoporosis was 67.3% and 15.2%, respectively, at the lumbar spine, and 43.4% and 10.8%, respectively, at the femur. After a GFD (n = 78), the prevalence of osteopenia and osteoporosis was 61.5% and 8.9%, respectively, at the lumbar spine, and 37.1% and 2.5%, respectively, at the femur. The prevalence of CD patients with low bone mineral density (BMD) is high after diagnosis and in the follow-up after a GFD. It is important for all patients with CD to undergo a DEXA scan to determine the follow-up and/or treatment characteristics.