Graphene films show stable cell attachment and biocompatibility with electrogenic primary cardiac cells

• Published in: Molecules and cells Vol. 36; no. 6; pp. 577 - 582
• Main Authors: Kim, T.O., Gwangju Institute of Science and Technology (GIST), Gwangju,Republic of Korea, Kahng, Y.H., Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea, Lee, T.H., Seoul National University, Seoul, Republic of Korea, Lee, K.H., Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea, Kim, D.H., Gwangju Institute of Science and Technology (GIST), Gwangju,Republic of Korea
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.12.2013; Korean Society for Molecular and Cellular Biology; Korea Society for Molecular and Cellular Biology; 한국분자세포생물학회
• Subjects: Animals; Biochemistry; Biocompatible Materials; Biomedical and Life Sciences; Biomedicine; Biotechnology; Calcium - metabolism; calcium transients,excitable cells,graphene; Cell Adhesion; Cell Biology; Cell Survival; Cells, Cultured; Graphite; Life Sciences; Male; Myocardial Contraction; Myocytes, Cardiac - physiology; Rats; Rats, Sprague-Dawley; Research Article; TOXICIDAD; TOXICITE; TOXICITY; 생물학; chemical vapor deposition; calcium transients; cytotoxicity; graphene; excitable cells
• ISSN: 1016-8478; 0219-1032
• DOI: 10.1007/s10059-013-0277-5

Graphene has attracted substantial attention due to its advantageous materialistic applicability. In the present study, we tested the biocompatibility of graphene films synthesized by chemical vapor deposition with electrogenic primary adult cardiac cells (cardiomyocytes) by measuring the cell properties such as cell attachment, survival, contractility and calcium transients. The results show that the graphene films showed stable cell attachment and excellent biocompatibility with the electrogenic cardiomyocytes, suggesting their useful applications for future cell biology studies.