Enzyme Activities of Liver Plasma Membrane in Rat Bile after the Intrabiliary Retrograde Infusion of Triton X-100
The activities of three bile canalicular enzymes, alkaline phosphatase, 5'-nucleotidase and ATPase, and protein concentration in bile were significantly elevated by the intrabiliary retrograde infusion of Triton X-100. The results suggest that a part of the bile canalicular site of the liver pl...
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Published in | Chemical & pharmaceutical bulletin Vol. 25; no. 6; pp. 1447 - 1449 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Tokyo
The Pharmaceutical Society of Japan
01.01.1977
Japan Science and Technology Agency |
Subjects | |
Online Access | Get full text |
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Summary: | The activities of three bile canalicular enzymes, alkaline phosphatase, 5'-nucleotidase and ATPase, and protein concentration in bile were significantly elevated by the intrabiliary retrograde infusion of Triton X-100. The results suggest that a part of the bile canalicular site of the liver plasma membrane was solubilized by the treatment. This explains the fact that the active biliary excretion of organic anions and cations was markedly inhibited by the same treatment. |
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ISSN: | 0009-2363 1347-5223 |
DOI: | 10.1248/cpb.25.1447 |