Polyubiquitination of Prolactin Receptor Stimulates Its Internalization, Postinternalization Sorting, and Degradation via the Lysosomal Pathway

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Published inMolecular and Cellular Biology Vol. 28; no. 17; pp. 5275 - 5287
Main Authors Varghese, Bentley, Barriere, Herve, Carbone, Christopher J., Banerjee, Anamika, Swaminathan, Gayathri, Plotnikov, Alexander, Xu, Ping, Peng, Junmin, Goffin, Vincent, Lukacs, Gergely L., Fuchs, Serge Y.
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.09.2008
Taylor & Francis
American Society for Microbiology (ASM)
Subjects
Adaptor Protein Complex 2 - metabolism
Cell Line
Clathrin - metabolism
Endocytosis - drug effects
Enzyme Inhibitors - pharmacology
Humans
Lysine - metabolism
Lysosomes - drug effects
Lysosomes - enzymology
Lysosomes - metabolism
Mass Spectrometry
Polyubiquitin - chemistry
Polyubiquitin - metabolism
Proteasome Inhibitors
Protein Binding - drug effects
Protein Processing, Post-Translational - drug effects
Receptors, Prolactin - metabolism
Ubiquitination - drug effects
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Summary:Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue MCB About MCB Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy MCB RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0270-7306 Online ISSN: 1098-5549 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to MCB .asm.org, visit: MCB       
Bibliography:B.V., H.B., and C.J.C. contributed equally to the manuscript.
Corresponding author. Mailing address: Department of Animal Biology and Mari Lowe Center for Comparative Oncology, School of Veterinary Medicine, University of Pennsylvania, 380 S. University Avenue, Room 316 Hill Pavilion, Philadelphia, PA 19104-4539. Phone: (215) 573-6949. Fax: (215) 746-2295. E-mail: syfuchs@vet.upenn.edu
ISSN:0270-7306
1098-5549
1098-5549
DOI:10.1128/MCB.00350-08