Signet-Ring Cutaneous Squamous Cell Carcinoma Arising on the Back of the Finger

A variety of pathologic variants of cutaneous squamous cell carcinoma (SCC) has been reported, and the signet-ring variant of cutaneous SCC is extremely uncommon. We reported an 83-year-old man with signet-ring SCC arising on the back of the finger. As far as we know, only 4 cases have been describe...

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Bibliographic Details
Published inCase reports in dermatology Vol. 5; no. 2; pp. 215 - 218
Main Authors Nakajima, Koji, Kaneko, Takahide, Aizu, Takayuki, Nakano, Hajime, Matsuzaki, Yasushi, Sawamura, Daisuke
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 10.08.2013
Karger Publishers
Subjects
Published: August, 2013
Signet-ring cell
Squamous cell carcinoma
Sun damage
Signet-ring cell
Squamous cell carcinoma
Sun damage
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Summary:A variety of pathologic variants of cutaneous squamous cell carcinoma (SCC) has been reported, and the signet-ring variant of cutaneous SCC is extremely uncommon. We reported an 83-year-old man with signet-ring SCC arising on the back of the finger. As far as we know, only 4 cases have been described in detail, and one dermatopathologic report focused on the presence of signet-ring cells briefly described in clinical data of 6 cases. Interestingly, in these reports, the skin lesions of 10 cases occurred exclusively in the head and neck area. This case involved a skin lesion on the back of the finger and is thus the first reported case of signet-cell cutaneous SCC that did not arise in the head and neck area. The location of this lesion, together with the histological findings compatible with actinic keratosis, support the hypothesis that the development of signet-ring SCC is related to ultraviolet light-induced damage.
ISSN:1662-6567
1662-6567
DOI:10.1159/000354536