Rodent models of cerebral ischemia
The use of physiologically regulated, reproducible animal models is crucial to the study of ischemic brain injury--both the mechanisms governing its occurrence and potential therapeutic strategies. Several laboratory rodent species (notably rats and gerbils), which are readily available at relativel...
Saved in:
| Published in | Stroke (1970) Vol. 20; no. 12; pp. 1627 - 1642 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
Hagerstown, MD
Lippincott Williams & Wilkins
01.12.1989
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The use of physiologically regulated, reproducible animal models is crucial to the study of ischemic brain injury--both the mechanisms governing its occurrence and potential therapeutic strategies. Several laboratory rodent species (notably rats and gerbils), which are readily available at relatively low cost, are highly suitable for the investigation of cerebral ischemia and have been widely employed for this purpose. We critically examine and summarize several rodent models of transient global ischemia, resulting in selective neuronal injury within vulnerable brain regions, and focal ischemia, typically giving rise to localized brain infarction. We explore the utility of individual models and emphasize the necessity for meticulous experimental control of those variables that modulate the severity of ischemic brain injury. |
|---|---|
| AbstractList | The use of physiologically regulated, reproducible animal models is crucial to the study of ischemic brain injury--both the mechanisms governing its occurrence and potential therapeutic strategies. Several laboratory rodent species (notably rats and gerbils), which are readily available at relatively low cost, are highly suitable for the investigation of cerebral ischemia and have been widely employed for this purpose. We critically examine and summarize several rodent models of transient global ischemia, resulting in selective neuronal injury within vulnerable brain regions, and focal ischemia, typically giving rise to localized brain infarction. We explore the utility of individual models and emphasize the necessity for meticulous experimental control of those variables that modulate the severity of ischemic brain injury.169 references. The use of physiologically regulated, reproducible animal models is crucial to the study of ischemic brain injury--both the mechanisms governing its occurrence and potential therapeutic strategies. Several laboratory rodent species (notably rats and gerbils), which are readily available at relatively low cost, are highly suitable for the investigation of cerebral ischemia and have been widely employed for this purpose. We critically examine and summarize several rodent models of transient global ischemia, resulting in selective neuronal injury within vulnerable brain regions, and focal ischemia, typically giving rise to localized brain infarction. We explore the utility of individual models and emphasize the necessity for meticulous experimental control of those variables that modulate the severity of ischemic brain injury. |
| Author | GINSBERG, M. D BUSTO, R |
| Author_xml | – sequence: 1 givenname: M. D surname: GINSBERG fullname: GINSBERG, M. D organization: Univ. Miami school medicine, cerebral vascular disease res. cent., Miami FL 33101, United States – sequence: 2 givenname: R surname: BUSTO fullname: BUSTO, R organization: Univ. Miami school medicine, cerebral vascular disease res. cent., Miami FL 33101, United States |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6694944$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/2688195$$D View this record in MEDLINE/PubMed https://www.osti.gov/biblio/5047078$$D View this record in Osti.gov |
| BookMark | eNo9kE1LAzEYhINUalv9AR6EUrzu-ubNxyZHKX5BQaj1HLLZhK7sR0nWg__eLS09DcM8M4eZk0nXd56Qewo5pZI-Ac3TEHMcLeZUYnFFZlQgz7hENSEzAKYz5FrfkHlKPwCATIkpmaJUimoxI6ttX_luWLajNGnZh6Xz0ZfRNss6ub1va3tLroNtkr8764J8v77s1u_Z5vPtY_28yZxANmSKUaoqxbT2lSiCRcTCAwu2EGhBAadBKKGZ51xUpXSlkhUEKZiUpeKg2IKsTrt9GmqTXD14t3d913k3GAG8gOII0RPkYp9S9MEcYt3a-GcomOMnBqj52m0NjhbN8ZOx83DqHH7L1leXxvmEMX885zY524RoO1enCyal5ppz9g91Dmhj |
| CODEN | SJCCA7 |
| CitedBy_id | crossref_primary_10_1007_BF00974874 crossref_primary_10_1016_j_bmc_2007_02_033 crossref_primary_10_1371_journal_pone_0026288 crossref_primary_10_1046_j_1440_1681_2002_03767_x crossref_primary_10_1097_01_WCB_0000034361_37277_1B crossref_primary_10_1016_1056_8719_92_90013_Q crossref_primary_10_4142_jvs_2018_19_4_505 crossref_primary_10_1016_S0022_510X_02_00302_7 crossref_primary_10_1016_j_brainres_2007_01_096 crossref_primary_10_1097_01_WCB_0000084252_20114_BE crossref_primary_10_1016_j_freeradbiomed_2005_03_028 crossref_primary_10_1097_00004647_199810000_00007 crossref_primary_10_1016_j_neuroscience_2011_06_022 crossref_primary_10_1097_00001756_200404290_00006 crossref_primary_10_1097_01_WCB_0000085160_71791_3F crossref_primary_10_1016_S0169_328X_02_00135_3 crossref_primary_10_1111_j_1365_2125_1992_tb05634_x crossref_primary_10_1111_j_1471_4159_2007_04990_x crossref_primary_10_12786_bn_2011_4_1_1 crossref_primary_10_1248_bpb_27_1561 crossref_primary_10_1007_s12975_013_0260_7 crossref_primary_10_17221_78_2017_VETMED crossref_primary_10_1111_j_1476_5381_2009_00256_x crossref_primary_10_1590_s0102_865020180080000001 crossref_primary_10_1016_j_neuro_2005_03_009 crossref_primary_10_3389_fneur_2020_01001 crossref_primary_10_1016_0006_8993_94_01436_L crossref_primary_10_1523_JNEUROSCI_18_06_02075_1998 crossref_primary_10_1016_0165_1838_94_90109_0 crossref_primary_10_1016_j_jneumeth_2003_12_024 crossref_primary_10_1016_0003_4975_96_00076_8 crossref_primary_10_1038_jcbfm_2012_101 crossref_primary_10_1016_S0006_8993_02_02263_1 crossref_primary_10_1007_BF01411178 crossref_primary_10_1517_14728222_2015_1021781 crossref_primary_10_1002_1099_1492_200005_13_3_154__AID_NBM620_3_0_CO_2_W crossref_primary_10_1179_016164105X18214 crossref_primary_10_1016_j_brainresbull_2016_02_016 crossref_primary_10_1161_STROKEAHA_114_008407 crossref_primary_10_1142_S0192415X03000916 crossref_primary_10_9758_cpn_2011_9_2_86 crossref_primary_10_1007_BF00593255 crossref_primary_10_1002_nbm_1940050104 crossref_primary_10_1213_ANE_0b013e3181d278f7 crossref_primary_10_1016_0014_2999_93_90363_M crossref_primary_10_1080_13880200802315659 crossref_primary_10_1016_0014_2999_94_90371_9 crossref_primary_10_1016_j_neuropharm_2004_07_002 crossref_primary_10_1097_00006123_199306000_00015 crossref_primary_10_1016_S0031_9384_98_00293_5 crossref_primary_10_1016_S0006_8993_00_02097_7 crossref_primary_10_1111_j_1399_6576_1994_tb03883_x crossref_primary_10_1007_s10571_011_9758_2 crossref_primary_10_1016_j_brainres_2005_12_024 crossref_primary_10_1016_S0306_4522_01_00145_2 crossref_primary_10_1007_BF02815084 crossref_primary_10_1016_0926_6917_95_90018_7 crossref_primary_10_1016_S0967_5868_95_80010_7 crossref_primary_10_1016_j_bcp_2006_11_009 crossref_primary_10_1016_j_neulet_2006_05_037 crossref_primary_10_1111_j_1749_6632_1995_tb16558_x crossref_primary_10_1016_S0300_9572_98_00128_2 crossref_primary_10_1016_j_brainres_2009_09_001 crossref_primary_10_1111_cns_12550 crossref_primary_10_1016_0006_8993_95_01454_3 crossref_primary_10_1016_j_brainres_2003_09_086 crossref_primary_10_1155_2014_919652 crossref_primary_10_1002_jnr_10380 crossref_primary_10_3109_00498259109043211 crossref_primary_10_1002_jmri_1213 crossref_primary_10_1016_S1052_3057_00_33693_X crossref_primary_10_1002_ddr_1189 crossref_primary_10_1523_JNEUROSCI_20_04_01358_2000 crossref_primary_10_1016_0028_3908_93_90019_Y crossref_primary_10_1016_S0006_8993_02_03543_6 crossref_primary_10_1179_016164101101198992 crossref_primary_10_1007_BF02674616 crossref_primary_10_1016_0014_2999_95_00846_2 crossref_primary_10_1016_j_envres_2017_08_029 crossref_primary_10_1016_j_neuroscience_2005_10_043 crossref_primary_10_1016_j_pneurobio_2003_08_002 crossref_primary_10_1016_S0736_5748_98_00089_6 crossref_primary_10_1002_ansa_202000169 crossref_primary_10_1016_0006_8993_94_01248_G crossref_primary_10_1097_01_WCB_0000073946_29308_55 crossref_primary_10_1177_1073858408322677 crossref_primary_10_1016_0197_0186_95_00118_2 crossref_primary_10_1016_j_pneurobio_2018_01_001 crossref_primary_10_1016_j_jstrokecerebrovasdis_2017_12_013 crossref_primary_10_1007_s12975_017_0554_2 crossref_primary_10_1016_0006_8993_92_90276_F crossref_primary_10_1016_0304_3940_94_90767_6 crossref_primary_10_1016_0006_8993_93_90992_V crossref_primary_10_1016_j_freeradbiomed_2020_12_018 crossref_primary_10_1590_S0102_86502002000900008 crossref_primary_10_1007_BF01345257 crossref_primary_10_1186_s12868_016_0327_y crossref_primary_10_1371_journal_pone_0124918 crossref_primary_10_1155_2016_1923160 crossref_primary_10_1364_BOE_5_001483 crossref_primary_10_1016_0006_8993_95_01158_7 crossref_primary_10_1046_j_1460_9568_2000_00984_x crossref_primary_10_1016_j_ijdevneu_2008_05_008 crossref_primary_10_1227_00006123_199207000_00014 crossref_primary_10_1155_2017_5868632 crossref_primary_10_1177_0271678X19827446 crossref_primary_10_7586_jkbns_2015_17_4_324 crossref_primary_10_1016_j_wjam_2019_04_008 crossref_primary_10_3389_fnins_2015_00458 crossref_primary_10_1016_j_surneu_2005_12_028 crossref_primary_10_1016_0014_2999_96_00387_1 crossref_primary_10_1111_j_1460_9568_1993_tb00947_x crossref_primary_10_1016_j_jstrokecerebrovasdis_2016_05_031 crossref_primary_10_1016_j_neuropharm_2007_08_010 crossref_primary_10_1016_S0169_328X_98_00263_0 crossref_primary_10_1016_0169_328X_96_00016_2 crossref_primary_10_1142_S0192415X03001296 crossref_primary_10_1016_0304_3940_92_90730_U crossref_primary_10_1016_j_neulet_2006_12_021 crossref_primary_10_1016_S0006_8993_98_00108_5 crossref_primary_10_1186_s13054_019_2600_9 crossref_primary_10_1016_S0149_7634_05_80182_4 crossref_primary_10_1016_0306_4522_95_00563_3 crossref_primary_10_1016_j_jneumeth_2007_06_029 crossref_primary_10_3171_jns_1992_77_2_0169 crossref_primary_10_1016_S0006_8993_98_00327_8 crossref_primary_10_1097_00004647_199906000_00009 crossref_primary_10_1038_sj_jcbfm_9600012 crossref_primary_10_1016_0300_9572_92_90194_H crossref_primary_10_1002_mnfr_200500019 crossref_primary_10_1016_j_jep_2020_113284 crossref_primary_10_52547_shefa_9_3_130 crossref_primary_10_1016_j_neulet_2003_10_009 crossref_primary_10_1089_neu_1995_12_943 crossref_primary_10_1016_j_neuroscience_2005_08_083 crossref_primary_10_1177_1073858407301681 crossref_primary_10_1523_JNEUROSCI_1666_06_2006 crossref_primary_10_1016_j_pathophys_2014_08_005 crossref_primary_10_1590_S0102_86502004000500012 crossref_primary_10_1007_BF00974572 crossref_primary_10_1117_1_JBO_19_9_096013 crossref_primary_10_1016_S0197_0186_97_00005_3 crossref_primary_10_1016_j_biopha_2017_02_109 crossref_primary_10_1016_S0006_8993_00_02693_7 crossref_primary_10_1002_nbm_1940070105 crossref_primary_10_1186_s12868_015_0179_x crossref_primary_10_1007_s12272_012_0116_9 crossref_primary_10_3803_EnM_2014_29_3_328 crossref_primary_10_1097_01_WCB_0000136517_61642_99 crossref_primary_10_1002_ddr_430270402 crossref_primary_10_1016_j_jneumeth_2005_02_013 crossref_primary_10_1016_S0306_3623_97_00284_X crossref_primary_10_1016_0014_2999_94_90337_9 crossref_primary_10_1038_sj_bjp_0703398 crossref_primary_10_1111_j_1749_6632_2001_tb03614_x crossref_primary_10_1007_s11655_014_1847_x crossref_primary_10_1016_j_brainres_2004_07_050 crossref_primary_10_1101_pdb_prot079509 crossref_primary_10_1254_jphs_10131FP crossref_primary_10_1523_JNEUROSCI_18_13_04891_1998 crossref_primary_10_1258_la_2007_006035 crossref_primary_10_3109_02699052_2013_865273 crossref_primary_10_1142_S0219635212500148 crossref_primary_10_1016_0006_8993_92_90267_D crossref_primary_10_1007_BF02740655 crossref_primary_10_2108_zsj_30_484 crossref_primary_10_1007_s12975_011_0067_3 crossref_primary_10_1016_0014_2999_95_00356_P crossref_primary_10_1016_S0014_2999_98_00100_9 crossref_primary_10_1155_2014_686109 crossref_primary_10_1097_00004647_200104000_00005 crossref_primary_10_1080_00207454_2021_1901695 crossref_primary_10_1016_j_bbr_2009_02_022 crossref_primary_10_1016_0006_8993_92_90990_Q crossref_primary_10_1038_jcbfm_2011_196 crossref_primary_10_1016_S0006_8993_96_01116_X crossref_primary_10_1016_S0952_3278_96_90012_5 crossref_primary_10_1007_s10753_019_01147_2 crossref_primary_10_1016_S0006_8993_97_00559_3 crossref_primary_10_1016_S0197_0186_02_00137_7 crossref_primary_10_1016_0928_0987_94_00073_9 crossref_primary_10_1038_jcbfm_2008_91 crossref_primary_10_1038_sj_bjp_0707574 crossref_primary_10_1016_j_niox_2005_01_003 crossref_primary_10_1016_S0033_0620_99_70002_2 crossref_primary_10_1007_s12975_012_0236_z crossref_primary_10_1016_j_neures_2022_06_007 crossref_primary_10_2220_biomedres_34_75 crossref_primary_10_1038_jcbfm_2009_56 crossref_primary_10_1177_0885328217722740 crossref_primary_10_1016_j_lfs_2006_12_022 crossref_primary_10_1007_BF03159984 crossref_primary_10_1016_S0091_3057_00_00469_X crossref_primary_10_1073_pnas_040577097 crossref_primary_10_1016_S0166_4328_96_02243_7 crossref_primary_10_3390_biom11081097 crossref_primary_10_1016_0091_3057_94_90501_0 crossref_primary_10_1186_2040_7378_1_7 crossref_primary_10_3892_mmr_2018_9503 crossref_primary_10_1016_j_neures_2008_01_008 crossref_primary_10_1093_jhered_esq066 crossref_primary_10_1556_JPC_24_2011_2_8 crossref_primary_10_1016_j_mri_2006_04_007 crossref_primary_10_1097_00006123_199603000_00021 crossref_primary_10_1002_0471142301_ns0905s12 crossref_primary_10_1017_S0317167100002444 crossref_primary_10_1111_j_1476_5381_2011_01398_x crossref_primary_10_1227_NEU_0b013e3182846f4c crossref_primary_10_1016_S0889_8529_05_70327_3 crossref_primary_10_1016_S0169_328X_01_00186_3 crossref_primary_10_1161_STROKEAHA_112_650416 crossref_primary_10_1016_0006_8993_95_01045_W crossref_primary_10_3233_JAD_170057 crossref_primary_10_1016_j_neulet_2006_02_020 crossref_primary_10_1016_S0300_9084_02_01381_0 crossref_primary_10_1111_j_1471_4159_2007_04526_x crossref_primary_10_1152_ajpregu_00755_2009 crossref_primary_10_1186_1423_0127_16_9 crossref_primary_10_1227_00006123_199401000_00005 crossref_primary_10_1016_0006_8993_92_91626_P crossref_primary_10_1016_0301_0082_95_00042_9 crossref_primary_10_1016_S1385_299X_02_00138_1 crossref_primary_10_1016_j_jocn_2020_09_023 crossref_primary_10_1038_jcbfm_1995_128 crossref_primary_10_1517_13543784_17_8_1161 crossref_primary_10_1016_0024_3205_96_00314_1 crossref_primary_10_1007_s11055_014_0032_1 crossref_primary_10_1016_0091_3057_94_90003_5 crossref_primary_10_1016_j_jep_2008_09_035 crossref_primary_10_1016_S0165_0270_98_00092_2 crossref_primary_10_1038_jcbfm_1995_129 crossref_primary_10_3892_mmr_2019_10828 crossref_primary_10_1016_0022_510X_96_00045_7 crossref_primary_10_1016_j_ejphar_2019_02_018 crossref_primary_10_1002_ddr_10330 crossref_primary_10_1111_j_1600_079X_2007_00551_x crossref_primary_10_1007_s12264_015_1567_z crossref_primary_10_3171_jns_2002_97_6_1410 crossref_primary_10_1016_S0165_6147_00_88999_3 crossref_primary_10_1007_s10571_009_9417_z crossref_primary_10_1016_j_neulet_2005_09_081 crossref_primary_10_1016_S0091_3057_96_00517_5 crossref_primary_10_1007_BF02887876 crossref_primary_10_1016_S0014_2999_97_01217_X crossref_primary_10_22494_COT_V1I1_51 crossref_primary_10_1016_j_jneumeth_2011_11_022 crossref_primary_10_1016_j_biopha_2019_108619 crossref_primary_10_1364_BOE_7_003377 crossref_primary_10_1177_0271678X21996175 crossref_primary_10_1016_0031_9384_94_90265_8 crossref_primary_10_1016_S0028_3908_99_00098_2 crossref_primary_10_1038_jcbfm_1995_18 crossref_primary_10_1177_026765910101600111 crossref_primary_10_1016_j_bjane_2015_03_009 crossref_primary_10_3892_etm_2017_4550 crossref_primary_10_1111_j_2042_7158_1998_tb04005_x crossref_primary_10_1007_s11064_014_1450_8 crossref_primary_10_1016_j_burns_2010_05_010 crossref_primary_10_1016_j_neuint_2018_11_002 crossref_primary_10_1097_00004647_199701000_00015 crossref_primary_10_1007_s11655_014_1782_2 crossref_primary_10_3109_00498259109039529 crossref_primary_10_1002_biof_552029202 crossref_primary_10_1016_0031_9384_94_90330_1 crossref_primary_10_1007_BF03258426 crossref_primary_10_1016_0165_3806_96_00098_3 crossref_primary_10_1016_j_jep_2011_01_033 crossref_primary_10_1016_S0165_0270_00_00351_4 crossref_primary_10_1038_jcbfm_1995_27 crossref_primary_10_1016_0006_8993_94_01407_9 crossref_primary_10_1038_jcbfm_1994_57 crossref_primary_10_1038_jcbfm_1993_87 crossref_primary_10_1016_S0014_4886_03_00116_X crossref_primary_10_1016_j_fct_2014_06_023 crossref_primary_10_1038_jcbfm_1994_138 crossref_primary_10_1586_erc_11_34 crossref_primary_10_1016_0006_8993_96_00400_3 crossref_primary_10_1155_2013_615154 crossref_primary_10_3171_jns_1995_83_6_1051 crossref_primary_10_1016_S0006_8993_03_02244_3 crossref_primary_10_1177_107385840000600110 crossref_primary_10_1038_jcbfm_1994_67 crossref_primary_10_1016_j_brainres_2017_08_008 crossref_primary_10_1016_j_jneumeth_2005_12_026 crossref_primary_10_1007_s11055_016_0359_x crossref_primary_10_1016_j_bjan_2015_12_006 crossref_primary_10_1038_jcbfm_1993_91 crossref_primary_10_1016_S0006_8993_97_00833_0 crossref_primary_10_1016_S0021_9150_99_00284_1 crossref_primary_10_1097_00006123_199207000_00014 crossref_primary_10_1155_2014_639531 crossref_primary_10_1016_S0165_0173_03_00170_X crossref_primary_10_1007_BF00294302 crossref_primary_10_1007_s12975_013_0267_0 crossref_primary_10_3171_jns_2000_92_5_0848 crossref_primary_10_1016_j_brainresrev_2005_07_003 crossref_primary_10_1016_0361_9230_93_90124_T crossref_primary_10_1016_0306_4522_91_90001_5 crossref_primary_10_1016_j_ajps_2016_07_008 crossref_primary_10_1002_ddr_10414 crossref_primary_10_6030_1939_067X_4_1_24 crossref_primary_10_1038_jcbfm_2011_8 crossref_primary_10_1007_BF02229081 crossref_primary_10_3171_2014_9_JNS14778 crossref_primary_10_1177_0748233713498461 crossref_primary_10_1016_0165_0270_95_00003_D crossref_primary_10_1016_j_jns_2004_07_021 crossref_primary_10_1016_j_pbb_2007_04_015 crossref_primary_10_1016_j_wneu_2022_09_043 crossref_primary_10_1006_nbdi_1998_0199 crossref_primary_10_1111_j_1476_5381_1995_tb16635_x crossref_primary_10_3390_ijms18112347 crossref_primary_10_1155_2011_803015 crossref_primary_10_1097_00006123_199401000_00005 crossref_primary_10_2463_mrms_2014_0039 crossref_primary_10_1016_j_jneumeth_2006_01_028 crossref_primary_10_1007_s11883_000_0112_2 crossref_primary_10_1016_S0361_9230_99_00186_0 crossref_primary_10_1016_S0006_8993_97_01414_5 crossref_primary_10_1016_0006_8993_92_90085_N crossref_primary_10_1177_088506669601100403 crossref_primary_10_1016_j_ncl_2005_10_004 crossref_primary_10_1016_S0006_8993_00_03011_0 crossref_primary_10_1016_S0361_9230_03_00028_5 crossref_primary_10_1016_j_medin_2013_03_015 crossref_primary_10_1016_j_expneurol_2017_03_004 crossref_primary_10_1002_jnr_490290309 crossref_primary_10_1016_0361_9230_91_90240_K crossref_primary_10_1093_bmb_65_1_235 crossref_primary_10_1227_00006123_199603000_00021 crossref_primary_10_1006_exnr_2000_7459 crossref_primary_10_1016_S1130_1473_00_70732_9 crossref_primary_10_1038_jcbfm_1993_108 crossref_primary_10_1016_S0014_2999_96_00891_6 crossref_primary_10_1124_jpet_103_064246 crossref_primary_10_1038_jcbfm_1993_100 crossref_primary_10_1007_BF00970534 crossref_primary_10_1016_S0031_9384_99_00111_0 crossref_primary_10_1016_j_neuroscience_2007_07_067 crossref_primary_10_1016_j_nucmedbio_2018_04_002 crossref_primary_10_1016_S1052_3057_96_80010_3 crossref_primary_10_1111_j_1747_4949_2012_00838_x crossref_primary_10_1097_00004647_200301000_00003 crossref_primary_10_1007_s11055_014_9958_6 crossref_primary_10_1093_bja_aem220 crossref_primary_10_1097_00004647_199904000_00008 crossref_primary_10_1016_j_biomaterials_2012_06_094 crossref_primary_10_1021_jf204909p crossref_primary_10_1016_S0166_4328_99_00162_X crossref_primary_10_1111_micc_12872 crossref_primary_10_1002__SICI_1099_1077_199607_11_4_299__AID_HUP772_3_0_CO_2_E crossref_primary_10_1016_0168_0102_93_90025_L crossref_primary_10_1016_1043_6618_92_90329_A crossref_primary_10_2176_nmc_51_337 crossref_primary_10_1007_s11011_019_00404_5 crossref_primary_10_1152_physrev_1999_79_4_1431 crossref_primary_10_1136_neurintsurg_2011_010101 crossref_primary_10_1016_S1130_1473_04_70495_9 crossref_primary_10_1111_j_1476_5381_1995_tb15110_x crossref_primary_10_1097_00004647_199609000_00020 crossref_primary_10_1016_j_brainresrev_2004_07_021 crossref_primary_10_1016_j_jns_2014_05_017 crossref_primary_10_1016_0197_0186_95_00086_0 crossref_primary_10_3390_cells8101126 crossref_primary_10_1254_jphs_FP0050872 crossref_primary_10_1007_s12200_013_0319_9 crossref_primary_10_1590_S0004_282X2007000600011 crossref_primary_10_1007_BF02592254 crossref_primary_10_1016_0031_9384_95_00103_P crossref_primary_10_1016_j_apradiso_2009_03_002 crossref_primary_10_1007_s11064_011_0696_7 crossref_primary_10_1016_0014_4886_92_90160_R crossref_primary_10_1016_S0006_8993_96_01285_1 crossref_primary_10_1002_ddr_10149 crossref_primary_10_1016_S0006_8993_99_02384_7 crossref_primary_10_1016_j_neuroscience_2012_10_042 crossref_primary_10_1016_S0022_510X_00_00434_2 crossref_primary_10_3233_RNN_150586 crossref_primary_10_1038_jcbfm_1992_133 crossref_primary_10_3171_jns_1997_87_5_0724 crossref_primary_10_1177_107385849500100206 crossref_primary_10_1007_BF02592245 crossref_primary_10_1038_jcbfm_2009_273 crossref_primary_10_1016_0006_8993_95_00033_M crossref_primary_10_1016_S0361_9230_96_00330_9 crossref_primary_10_1038_jcbfm_1993_15 crossref_primary_10_1016_j_brainres_2004_05_098 crossref_primary_10_1080_01616412_2017_1315499 crossref_primary_10_1096_fj_05_3793com crossref_primary_10_1186_1742_2094_3_12 crossref_primary_10_1016_0024_3205_95_02034_G crossref_primary_10_1093_ilar_44_2_85 crossref_primary_10_1080_1028415021000055952 crossref_primary_10_1088_1741_2560_3_4_L01 crossref_primary_10_1016_j_lfs_2003_11_013 crossref_primary_10_1016_S0091_3057_96_00409_1 crossref_primary_10_1016_j_neulet_2003_09_079 crossref_primary_10_1007_BF01400874 crossref_primary_10_1016_S0301_0082_98_00085_9 crossref_primary_10_1097_00006123_199908000_00027 crossref_primary_10_1016_j_brainres_2007_08_038 crossref_primary_10_6116_kjh_2012_27_6_71 crossref_primary_10_1016_S0028_3908_98_00008_2 crossref_primary_10_1016_0006_8993_95_00516_S crossref_primary_10_1016_j_neuroscience_2008_06_018 crossref_primary_10_1111_j_1747_4949_2012_00802_x crossref_primary_10_1016_j_jneumeth_2006_09_017 crossref_primary_10_1093_ilar_44_2_96 crossref_primary_10_1097_00000441_199501000_00007 crossref_primary_10_1093_ilar_45_2_147 crossref_primary_10_6116_kjh_2012_27_6_83 crossref_primary_10_1016_0197_0186_95_00065_8 crossref_primary_10_1016_0169_328X_94_90074_4 crossref_primary_10_1016_S0733_8619_18_30233_0 |
| ContentType | Journal Article |
| Copyright | 1990 INIST-CNRS |
| Copyright_xml | – notice: 1990 INIST-CNRS |
| DBID | IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION OTOTI |
| DOI | 10.1161/01.str.20.12.1627 |
| DatabaseName | Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef OSTI.GOV |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef |
| DatabaseTitleList | MEDLINE CrossRef |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1524-4628 |
| EndPage | 1642 |
| ExternalDocumentID | 5047078 10_1161_01_STR_20_12_1627 2688195 6694944 |
| Genre | Research Support, U.S. Gov't, P.H.S Journal Article Review |
| GrantInformation_xml | – fundername: NINDS NIH HHS grantid: NS-22603 – fundername: NINDS NIH HHS grantid: NS-05820 |
| GroupedDBID | --- .3C .55 .GJ .XZ .Z2 01R 08R 0R~ 123 1J1 2WC 3O- 40H 4Q1 4Q2 4Q3 53G 5RE 5VS 6PF 71W 77Y 7O~ A9M AAAXR AAGIX AAHPQ AAJCS AAMOA AAMTA AAPBV AAQKA AAQQT AARTV AASOK AAUGY AAXQO AAYEP AAYJJ ABASU ABBUW ABDIG ABQRW ABXVJ ABZAD ACCJW ACDDN ACEWG ACGFS ACGOD ACILI ACWDW ACWRI ACXNZ ADBBV ADFPA ADGGA ADNKB AE3 AE6 AEBDS AEETU AENEX AFDTB AFFNX AFUWQ AGINI AHMBA AHOMT AHRYX AHVBC AIJEX AJIOK AJNWD AJNYG AKALU AKULP ALMA_UNASSIGNED_HOLDINGS ALMTX AMJPA AMKUR AMNEI AOHHW AWKKM AYCSE BAWUL BCGUY BOYCO BQLVK BS7 C45 CS3 DIK DIWNM DU5 DUNZO E.X E3Z EBS EEVPB EJD EX3 F2K F2L F2M F2N F5P FCALG FL- FW0 GNXGY GQDEL GX1 H0~ H13 HZ~ IKREB IKYAY IN~ IPNFZ IQODW J5H JF9 JG8 JK3 JK8 K8S KD2 KMI KQ8 L-C L7B M18 N4W N9A N~7 N~B N~M O9- OAG OAH OB3 OCUKA ODA ODMTH OGROG OHYEH OJAPA OK1 OL1 OLG OLH OLU OLV OLW OLY OLZ OPUJH ORVUJ OUVQU OVD OVDNE OVIDH OVLEI OVOZU OWBYB OWU OWV OWW OWX OWY OWZ OXXIT P-K P2P PQQKQ R58 RAH RHF RIG RLZ S4R S4S T8P TEORI TSPGW TWZ V2I VVN W3M W8F WH7 WOQ WOW X3V X3W X7M XXN XYM YCJ YFH YHZ YQJ YYP ZA5 ZB8 ZGI ZZMQN AAAAV AAIQE AASCR AAUEB ABJNI ABVCZ ACLDA ACXJB ADHPY AFEXH AFSOK AHQNM AINUH AJZMW CGR CUY CVF ECM EIF ERAAH HLJTE NPM AAYXX CITATION OTOTI PQEST |
| ID | FETCH-LOGICAL-c523t-83118d8399ed57fa2227e03fa752a08041f58593e445db6cb86d0f65366b84083 |
| ISSN | 0039-2499 |
| IngestDate | Thu May 18 22:23:56 EDT 2023 Fri Aug 23 02:01:30 EDT 2024 Wed Oct 16 00:51:46 EDT 2024 Sun Oct 29 17:08:43 EDT 2023 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 12 |
| Keywords | Brain Animal model Vertebrata Nervous system diseases Mammalia Ischemia Animal Rodentia Bibliographic survey Technique Cerebrovascular disease |
| Language | English |
| License | CC BY 4.0 |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c523t-83118d8399ed57fa2227e03fa752a08041f58593e445db6cb86d0f65366b84083 |
| OpenAccessLink | https://www.ahajournals.org/doi/pdf/10.1161/01.STR.20.12.1627 |
| PMID | 2688195 |
| PageCount | 16 |
| ParticipantIDs | osti_scitechconnect_5047078 crossref_primary_10_1161_01_STR_20_12_1627 pubmed_primary_2688195 pascalfrancis_primary_6694944 |
| PublicationCentury | 1900 |
| PublicationDate | 1989-12-01 |
| PublicationDateYYYYMMDD | 1989-12-01 |
| PublicationDate_xml | – month: 12 year: 1989 text: 1989-12-01 day: 01 |
| PublicationDecade | 1980 |
| PublicationPlace | Hagerstown, MD |
| PublicationPlace_xml | – name: Hagerstown, MD – name: United States |
| PublicationTitle | Stroke (1970) |
| PublicationTitleAlternate | Stroke |
| PublicationYear | 1989 |
| Publisher | Lippincott Williams & Wilkins |
| Publisher_xml | – name: Lippincott Williams & Wilkins |
| SSID | ssj0002385 |
| Score | 1.9170356 |
| SecondaryResourceType | review_article |
| Snippet | The use of physiologically regulated, reproducible animal models is crucial to the study of ischemic brain injury--both the mechanisms governing its occurrence... |
| SourceID | osti crossref pubmed pascalfrancis |
| SourceType | Open Access Repository Aggregation Database Index Database |
| StartPage | 1627 |
| SubjectTerms | 550901 - Pathology- Tracer Techniques ANIMALS ANOXIA Arterial Occlusive Diseases - complications ARTERIES BASIC BIOLOGICAL SCIENCES Biological and medical sciences BIOLOGICAL MATERIALS BIOLOGICAL MODELS BLOOD VESSELS BODY BODY FLUIDS BRAIN Brain Ischemia - etiology Brain Ischemia - physiopathology CARDIOVASCULAR DISEASES CARDIOVASCULAR SYSTEM CENTRAL NERVOUS SYSTEM Cerebral Arteries CEREBROSPINAL FLUID Cerebrospinal Fluid Pressure Cerebrovascular Disorders - etiology Disease Models, Animal DISEASES DOCUMENT TYPES Gerbillinae Hypoxia, Brain - etiology Intracranial Embolism and Thrombosis - chemically induced ISCHEMIA ISOTOPE APPLICATIONS Light MAMMALS MATERIALS Medical sciences NERVOUS SYSTEM Nervous system involvement in other diseases. Miscellaneous Neurology Neurology - methods ORGANS PATHOGENESIS Radiation-Sensitizing Agents RATS Rats, Inbred SHR REVIEWS RODENTS THROMBOSIS TRACER TECHNIQUES VASCULAR DISEASES VERTEBRATES |
| Title | Rodent models of cerebral ischemia |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/2688195 https://www.osti.gov/biblio/5047078 |
| Volume | 20 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3fa9swEBZrBqUvY90amnUtZvRpxakt24r12I6tYSOFtgn0zciyBKFtXBLnpX997yQ5dn_BUggmccjF1mefvrO-uyPkUMAUJ1Ug_QS4BLYwEz5XLPep4FIqHuXUJImNztlwEv-9Tq6bfnkmu6TK-_Lh1byS96AK-wBXzJJdA9mVUdgB7wFf2ALCsP0vjC9LTLO13WyMJEOqOS4E3x5NIWhVd1PR5p5X1by8MZQy5IOg9QjgbDpb1DKvUSMBPl0uTI8lpyksRK19amQWzt1FuHxiOxD1lfNwNPYxIbXtAmnQhpq2HFrIbOq-mxwhuKKvO14WmmSC_tX4EqJufMTa_LRd5PrZ5LOSBJpghIVZEGZgIqPwkWZoYoN8pOBE0Hv9u2gqwQPVsN0p3Cm6FWswcfziKJ5wjk4JvhMlsGIBd4G27UueBRWGXIw_k08uKvBOLMTb5IOafSGbI6d7-Ep-WKQ9i7RXaq9G2quR3iGTP7_Hv4a-627hSwj-Kz-NILYrgJ9yVSQDLTApWQWRFoOEigDLQukEi9GpOE6KnMk8ZUWgWRIxlkNUnkZd0pmVM7VLPMp1UQgJobTkMS_gBcQtFVLDbRilmvfIz_r8s3tbxCR7c7x7ZA9HKAMGhmWEJeqtZJUlQYyFoXpk_8nArewxBn8dxz3StQO5-oKyFNdqv61zDHtkq7mev5NONV-qfSB_VX5groJHXbtNnw |
| link.rule.ids | 230,315,783,787,888,27936,27937 |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Rodent+models+of+cerebral+ischemia&rft.jtitle=Stroke+%281970%29&rft.au=Ginsberg%2C+M+D&rft.au=Busto%2C+R&rft.date=1989-12-01&rft.issn=0039-2499&rft.eissn=1524-4628&rft.volume=20&rft.issue=12&rft.spage=1627&rft.epage=1642&rft_id=info:doi/10.1161%2F01.STR.20.12.1627&rft.externalDBID=n%2Fa&rft.externalDocID=10_1161_01_STR_20_12_1627 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0039-2499&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0039-2499&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0039-2499&client=summon |