Day-to-day reciprocal associations between depressive symptoms, cognitive performance, and sleep and the single-subject design

Reciprocal associations between major depressive disorder and cognitive impairment as well as between depression or cognitive decline and impaired sleep have been widely recognized. [...]in many cases, impaired sleep is the chief complaint of depression, and vice versa, several longitudinal studies...

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Published inInternational psychogeriatrics Vol. 34; no. 1; pp. 7 - 9
Main Authors Rosenblum, Yevgenia, Claassen, Jurgen A. H. R.
Format Journal Article
LanguageEnglish
Published Cambridge, UK Cambridge University Press 01.01.2022
Elsevier Inc
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Summary:Reciprocal associations between major depressive disorder and cognitive impairment as well as between depression or cognitive decline and impaired sleep have been widely recognized. [...]in many cases, impaired sleep is the chief complaint of depression, and vice versa, several longitudinal studies have identified insomnia as an independent risk factor for the development of emerging or recurrent depression (Fang et al., 2019). Neuroinflammation, in turn, is implicated in contributing to a variety of illnesses, including Alzheimer’s disease, Parkinson’s disease, and depression. [...]far, most literature has focused on long-term associations between mood, sleep, and cognitive performance (in all possible combinations). While the current study by Zuidersma and colleagues highlights the importance of considering day-to-day relationships between mood, cognition, and sleep, it could not provide any information on the mechanism of the reported associations. [...]other future considerations for the present work may include the use of objective measures or interventions, for example, polysomnography, more comprehensive assessments of cognition, auditory closed-loop stimulation, and pharmacological interventions.
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ISSN:1041-6102
1741-203X
1741-203X
DOI:10.1017/S1041610221001149