Circulating Tumor Cells as a Potential Biomarker in Selecting Patients for Pulmonary Metastasectomy from Colorectal Cancer:Report of a Case

Pulmonary metastasectomy is indicated for selected patients with metastatic colorectal cancer. A 43-year-old woman presented with solitary pulmonary metastasis from descending colon cancer and pulmonary metastasectomy was performed because of absence of any other active metastasis as well as normal...

Full description

Saved in:
Bibliographic Details
Published inCase reports in oncology Vol. 5; no. 3; pp. 542 - 545
Main Authors Hashimoto, M., Tanaka, F., Yoneda, K., Kondo, N., Takuwa, T., Matsumoto, S., Kuroda, A., Noda, M., Tomita, N., Hasegawa, S.
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 10.10.2012
Karger Publishers
Subjects
Circulating tumor cells
Colorectal cancer
Published: October 2012
Pulmonary metastasectomy
Pulmonary metastasectomy
Colorectal cancer
Circulating tumor cells
Online AccessGet full text

Cover

More Information
Summary:Pulmonary metastasectomy is indicated for selected patients with metastatic colorectal cancer. A 43-year-old woman presented with solitary pulmonary metastasis from descending colon cancer and pulmonary metastasectomy was performed because of absence of any other active metastasis as well as normal serum carcinoembryonic antigen value. However, she died due to early development of nodal and bone metastases within 6 months after thoracotomy. The presence of circulating tumor cells (CTCs) in the peripheral blood (6 CTCs/7.5 ml) was the only factor to predict such a poor prognosis, suggesting that the CTC test is useful in selecting patients for pulmonary metastasectomy.
ISSN:1662-6575
1662-6575
DOI:10.1159/000343677