IL-13 may be involved in the development of CAD via different mechanisms under different conditions in a Chinese Han population

• Published in: Scientific reports Vol. 8; no. 1; pp. 6182 - 8
• Main Authors: Zha, Ling-Feng, Nie, Shao-Fang, Chen, Qian-Wen, Liao, Yu-Hua, Zhang, Hong-Song, Dong, Jiang-Tao, Xie, Tian, Wang, Fan, Tang, Ting-Ting, Xia, Ni, Xu, Cheng-Qi, Zhou, Ying-Chao, Zeng, Zhi-Peng, Jiao, Jiao, Wang, Peng-Yun, Wang, Qing K., Tu, Xin, Cheng, Xiang
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 18.04.2018; Nature Publishing Group
• Subjects: 13/21; 45/43; 45/77; 692/4019/592/2727; 692/499; Arteriosclerosis; Cardiovascular disease; Coronary artery; Haplotypes; Health risk assessment; Heart diseases; Humanities and Social Sciences; Interleukin 1; Interleukin 13; multidisciplinary; Population; Risk factors; Science; Science (multidisciplinary); Single-nucleotide polymorphism

Interleukin-13 (IL-13) has important functions in atherosclerosis, but its role in coronary artery disease (CAD) is unclear. Here, we studied the genetic role of IL-13 in CAD in a Chinese Han population using tag SNPs covering the whole IL13 gene (i.e., rs1881457, rs2069744 and rs20541) and a two-st...