Smartphone-Based Multiplexed Biosensing Tools for Health Monitoring

• Published in: Biosensors (Basel) Vol. 12; no. 8; p. 583
• Main Authors: Beduk, Tutku, Beduk, Duygu, Hasan, Mohd Rahil, Guler Celik, Emine, Kosel, Jurgen, Narang, Jagriti, Salama, Khaled Nabil, Timur, Suna
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 29.07.2022; MDPI
• Subjects: Actuators; Artificial intelligence; Biomarkers; Biosensors; Cameras; Cancer; clinical diagnosis; Communication; Design and construction; Diagnosis; Digital imaging; Disease; electrochemical sensor; Electrochemistry; Health care; Interfaces; Internet of Things; Laboratories; Medical diagnosis; Medical research; Metabolites; multiplexed detection; Multiplexers; Multiplexing; New technology; Pathogens; Patient monitoring equipment; Patients; Personal health; Portable equipment; Review; Sensors; Signal processing; Smart phones; smartphone-based detection; Smartphones; Telemedicine; User interfaces; Wireless access points; Wireless communications; Netherlands
• ISSN: 2079-6374; 2079-6374
• DOI: 10.3390/bios12080583

Many emerging technologies have the potential to improve health care by providing more personalized approaches or early diagnostic methods. In this review, we cover smartphone-based multiplexed sensors as affordable and portable sensing platforms for point-of-care devices. Multiplexing has been gaining attention recently for clinical diagnosis considering certain diseases require analysis of complex biological networks instead of single-marker analysis. Smartphones offer tremendous possibilities for on-site detection analysis due to their portability, high accessibility, fast sample processing, and robust imaging capabilities. Straightforward digital analysis and convenient user interfaces support networked health care systems and individualized health monitoring. Detailed biomarker profiling provides fast and accurate analysis for disease diagnosis for limited sample volume collection. Here, multiplexed smartphone-based assays with optical and electrochemical components are covered. Possible wireless or wired communication actuators and portable and wearable sensing integration for various sensing applications are discussed. The crucial features and the weaknesses of these devices are critically evaluated.