atg7-Based Autophagy Activation Reverses Doxorubicin-Induced Cardiotoxicity

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Bibliographic Details
Published inCirculation research Vol. 129; no. 8; pp. e166 - e182
Main Authors Wang, Yong, Lu, Xiaoguang, Wang, Xiaoping, Qiu, Qi, Zhu, Ping, Ma, Lin, Ma, Xiao, Herrmann, Joerg, Lin, Xueying, Wang, Wei, Xu, Xiaolei
Format Journal Article
LanguageEnglish
Published United States Lippincott Williams & Wilkins 01.10.2021
Subjects
Animals
Antineoplastic Agents - toxicity
Autophagy - drug effects
Autophagy-Related Protein 7 - genetics
Autophagy-Related Protein 7 - metabolism
Cardiotoxicity
Doxorubicin - toxicity
Myocarditis - drug therapy
Myocarditis - etiology
Myocarditis - metabolism
Pravastatin - pharmacology
Pravastatin - therapeutic use
Spironolactone - pharmacology
Spironolactone - therapeutic use
Zebrafish
Zebrafish Proteins - genetics
Zebrafish Proteins - metabolism
cardiotoxicity
autophagy
doxorubicin
zebrafish
anthracycline
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Summary:[Figure: see text].
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These authors contributed equally to this work.
ISSN:0009-7330
1524-4571
1524-4571
DOI:10.1161/CIRCRESAHA.121.319104