Genome typing of nonhuman primate models: implications for biomedical research

Highlights • Currently, full consideration is not being given to the genetic variation in nonhuman primates (NHP). • As models for human disease, it is critical to understand how genetic variation in NHPs affects biomedical research. • The sequencing of NHP genomes is enabling advances in assessing...

Full description

Saved in:
Bibliographic Details
Published inTrends in genetics Vol. 30; no. 11; pp. 482 - 487
Main Authors Haus, Tanja, Ferguson, Betsy, Rogers, Jeffrey, Doxiadis, Gaby, Certa, Ulrich, Rose, Nicola J, Teepe, Robert, Weinbauer, Gerhard F, Roos, Christian
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.11.2014
Subjects
Animals
Biomedical Research - methods
Biomedical Research - trends
biomedicine
breeding management
Disease Models, Animal
Genetic Variation
Genome-Wide Association Study - methods
Genome-Wide Association Study - trends
genomics
Genomics - methods
Genomics - trends
genotyping
Humans
Medical Education
Precision Medicine - methods
Precision Medicine - trends
Primates
Sequence Analysis, DNA - methods
Sequence Analysis, DNA - trends
genomics
genetic variation
biomedicine
primates
breeding management
genotyping
Online AccessGet full text

Cover

More Information
Summary:Highlights • Currently, full consideration is not being given to the genetic variation in nonhuman primates (NHP). • As models for human disease, it is critical to understand how genetic variation in NHPs affects biomedical research. • The sequencing of NHP genomes is enabling advances in assessing and leveraging genetic variation. • Guidelines are needed to improve biomedical research and breeding practices.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0168-9525
DOI:10.1016/j.tig.2014.05.004