The Identification of CTX-M-14, TEM-52, and CMY-1 Enzymes in Escherichia coli Isolated from the Han River in Korea

• Published in: The journal of microbiology Vol. 46; no. 5; pp. 478 - 481
• Main Authors: Kim, J.M. (Kyungpook National University, Daegu, Republic of Korea), E-mail: minkim@knu.ac.kr, Kang, H.Y. (Kyungpook National University, Daegu, Republic of Korea), Lee, Y.H. (Seoul Women's University, Seoul, Republic of Korea)
• Format: Journal Article
• Language: English
• Published: Heidelberg The Microbiological Society of Korea 01.10.2008; Springer Nature B.V; 한국미생물학회
• Subjects: Antibiotics; Antimicrobial agents; Bacteria; beta-Lactamases - genetics; Biomedical and Life Sciences; CMY-1; CTX-M-14; Drug resistance; Drug Resistance, Bacterial; E coli; E. coli from river water; ESCHERICHIA COLI; Escherichia coli - enzymology; Escherichia coli - genetics; Escherichia coli - isolation & purification; Escherichia coli Proteins - genetics; Fresh Water - microbiology; Integrons; Korea; Life Sciences; Microbiology; Rivers; TEM-52; Water analysis; Water sampling; 생물학; Korea; South Korea; Han River; TEM-52; CTX-M-14; from river water; CMY-1
• ISSN: 1225-8873; 1976-3794
• DOI: 10.1007/s12275-008-0150-y

From water samples collected monthly between 2000 and 2001 from the Han River in Seoul, sixteen strains of Escherichia coli which confer resistance to at least 10 kinds of antimicrobial agents were isolated. From these isolates, 2 kinds of extended-spectrum β-lactamases (ESBLs) and one plasmid-mediated AmpC β-lactamase were detected; CTX-M-14 from 10 isolates, TEM-52 from 5 isolates, and CMY-1 from one isolate. Class 1 integron gene cassettes, such as aadA1, dfr12-orfF-aadA2, and dfr17-aadA5, were also detected and the integrons are the same as those found in E. coli isolated from swine, poultry, and humans in Korea. The result of this study indicated the importance of river water as a reservoir for antimicrobial resistance genes and resistant bacteria.