The dark side of SARS-CoV-2 rapid antigen testing: screening asymptomatic patients

Several reports showed SARS-CoV-2 rapid antigen tests (RATs) performances among COVID-19 symptomatic subjects in outpatient settings during periods of highest incidence of infections and high rates of hospital admissions, but few data are present for asymptomatic patients. We investigated the role o...

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Published inNew microbes and new infections Vol. 42; p. 100899
Main Authors Caruana, G., Lebrun, L.-L., Aebischer, O., Opota, O., Urbano, L., de Rham, M., Marchetti, O., Greub, G.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.07.2021
Elsevier
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Summary:Several reports showed SARS-CoV-2 rapid antigen tests (RATs) performances among COVID-19 symptomatic subjects in outpatient settings during periods of highest incidence of infections and high rates of hospital admissions, but few data are present for asymptomatic patients. We investigated the role of RATs in an emergency department, as a novel screening tool before admission for COVID-19 asymptomatic patients. A total of 116 patients were screened on admission in a 250-bed community hospital in Morges, Switzerland. RAT detected 2/7 RT-PCR-positive patients and delivered two false-positive results. These data suggest the non-fiability of RATs screening in this clinical scenario.
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G.G. and O.M. contributed equally.
ISSN:2052-2975
2052-2975
DOI:10.1016/j.nmni.2021.100899