Microbiome: Focus on Causation and Mechanism

There is tremendous enthusiasm for the microbiome in academia and industry. This Perspective argues that in order to realize its potential, the field needs to focus on establishing causation and molecular mechanism with an emphasis on phenotypes that are large in magnitude, easy to measure, and unam...

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Bibliographic Details
Published inCell Vol. 174; no. 4; pp. 785 - 790
Main Author Fischbach, Michael A.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 09.08.2018
Subjects
Bacterial Infections - diagnosis
Bacterial Infections - microbiology
Bacterial Infections - prevention & control
Humans
Microbiota
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Summary:There is tremendous enthusiasm for the microbiome in academia and industry. This Perspective argues that in order to realize its potential, the field needs to focus on establishing causation and molecular mechanism with an emphasis on phenotypes that are large in magnitude, easy to measure, and unambiguously driven by the microbiota. The microbiome field, argues this Perspective, needs to focus on establishing causation and molecular mechanism, with an emphasis on phenotypes that are large in magnitude, easy to measure, and unambiguously driven by the microbiota.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2018.07.038