A high-throughput liquid bead array assay confirms strong correlation between SARS-CoV-2 antibody level and COVID-19 severity

• Published in: iScience Vol. 24; no. 2; p. 102052
• Main Authors: Bennett, Monique, Yoder, Sandra, Brady, Eric, Pulley, Jill M., Rhoads, Jillian P., Stewart, Thomas G., Bernard, Gordon R., Creech, C. Buddy, Wheeler, Allison P., Thomsen, Isaac
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 19.02.2021; Elsevier
• Subjects: Biological Sciences; Microbiology; Viral Microbiology; Virology; Biological Sciences; Viral Microbiology; Microbiology; Virology

A detailed understanding of the adaptive host response to SARS-CoV-2 infection in humans is urgently needed. We developed a sensitive, high-throughput, and efficient assay using liquid bead array technology. We observed advantages over traditional ELISA for the detection and quantification of bindin...