Effects of Antidromic Stimulation of the Ventral Root on Glucose Utilization in the Ventral Horn of the Spinal Cord in the Rat

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 84; no. 15; pp. 5492 - 5495
• Main Authors: Kadekaro, Massako, Vance, W. Hugh, Terrell, Mary Lee, Gary, Howard, Eisenberg, Howard M., Sokoloff, Louis
• Format: Journal Article
• Language: English
• Published: Washington, DC National Academy of Sciences of the United States of America 01.08.1987; National Acad Sciences
• Subjects: Action potentials; Animals; Biological and medical sciences; Blood; Blood plasma; Cell physiology; Cellular metabolism; Electric Stimulation; Electrical stimulation; Electrophysiology; Evoked Potentials; Fundamental and applied biological sciences. Psychology; Glucose - metabolism; Male; Molecular and cellular biology; Neurons; Neurotransmission; Rats; Rats, Inbred Strains; Sciatic nerve; Sciatic Nerve - physiology; Spinal cord; Spinal Cord - metabolism; Spinal Nerve roots; Synapses; Biodegradation; Spinal cord; Rat; Electrical activity; Anterior spinal root; Rodentia; Axon; Anterior spinal horn; Glucose; Metabolism; Vertebrata; Mammalia; Neuron; Animal
• ISSN: 0027-8424; 1091-6490
• DOI: 10.1073/pnas.84.15.5492

Electrical stimulation of the proximal stump of the transected sciatic nerve increased glucose utilization in the ventral horn of the spinal cord, with the greater increase in Rexed's lamina IX. Antidromic stimulation of the ventral root, however, did not change glucose utilization in the ventral horn. These results suggest that the axon terminals and not the cell bodies are the sites of enhanced metabolic activity during increased electrical activity in these elements.