Mucositis and oral infections secondary to gram negative rods in patients with prolonged neutropenia

Patients with prolonged neutropenia are at risk for a variety of complications and infections including the development of mucositis and oral ulcers. The changes in oral flora during chemotherapy and its effects on the development of infections of the oral cavity have been studied with inconsistent...

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Published inIDCases Vol. 9; no. C; pp. 101 - 103
Main Authors Sampson, Mindy M., Nanjappa, Sowmya, Greene, John N.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.01.2017
Elsevier
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Abstract Patients with prolonged neutropenia are at risk for a variety of complications and infections including the development of mucositis and oral ulcers. The changes in oral flora during chemotherapy and its effects on the development of infections of the oral cavity have been studied with inconsistent results. However, there is evidence that supports the colonization of gram negative rods in patients undergoing chemotherapy. In this report, we present two leukemic patients who developed oral ulcers secondary to multi-drug resistant Pseudomonas aeruginosa. It is important to suspect multi-drug resistant gram negative rods in patients with prolonged neutropenia who develop gum infections despite appropriate antibiotic coverage.
AbstractList Patients with prolonged neutropenia are at risk for a variety of complications and infections including the development of mucositis and oral ulcers. The changes in oral flora during chemotherapy and its effects on the development of infections of the oral cavity have been studied with inconsistent results. However, there is evidence that supports the colonization of gram negative rods in patients undergoing chemotherapy. In this report, we present two leukemic patients who developed oral ulcers secondary to multi-drug resistant Pseudomonas aeruginosa. It is important to suspect multi-drug resistant gram negative rods in patients with prolonged neutropenia who develop gum infections despite appropriate antibiotic coverage.
Author Sampson, Mindy M.
Nanjappa, Sowmya
Greene, John N.
AuthorAffiliation b Department of Internal Medicine and Department of Oncologic Sciences, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, United States
c Infectious Diseases and Hospital Epidemiologist, H. Lee Moffitt Cancer Center and Research Institute,12902, Magnolia Drive, FOB-3, United States
a Department of Internal Medicine, University of South Florida, 17 Davis Blvd., Suite 308, 33606 Tampa, FL, United States
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Issue C
Keywords Resistant Pseudomonas aeruginosa
Mucositis
Neutropenia
Language English
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Snippet Patients with prolonged neutropenia are at risk for a variety of complications and infections including the development of mucositis and oral ulcers. The...
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SubjectTerms Case Report
Mucositis
Neutropenia
Resistant Pseudomonas aeruginosa
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Title Mucositis and oral infections secondary to gram negative rods in patients with prolonged neutropenia
URI https://dx.doi.org/10.1016/j.idcr.2017.06.014
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