Mucositis and oral infections secondary to gram negative rods in patients with prolonged neutropenia

Patients with prolonged neutropenia are at risk for a variety of complications and infections including the development of mucositis and oral ulcers. The changes in oral flora during chemotherapy and its effects on the development of infections of the oral cavity have been studied with inconsistent...

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Published inIDCases Vol. 9; no. C; pp. 101 - 103
Main Authors Sampson, Mindy M., Nanjappa, Sowmya, Greene, John N.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.01.2017
Elsevier
Subjects
Case Report
Mucositis
Neutropenia
Resistant Pseudomonas aeruginosa
Resistant Pseudomonas aeruginosa
Mucositis
Neutropenia
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Summary:Patients with prolonged neutropenia are at risk for a variety of complications and infections including the development of mucositis and oral ulcers. The changes in oral flora during chemotherapy and its effects on the development of infections of the oral cavity have been studied with inconsistent results. However, there is evidence that supports the colonization of gram negative rods in patients undergoing chemotherapy. In this report, we present two leukemic patients who developed oral ulcers secondary to multi-drug resistant Pseudomonas aeruginosa. It is important to suspect multi-drug resistant gram negative rods in patients with prolonged neutropenia who develop gum infections despite appropriate antibiotic coverage.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:2214-2509
2214-2509
DOI:10.1016/j.idcr.2017.06.014