Metabolism, signaling, and transport of jasmonates

• Published in: Plant communications Vol. 2; no. 5; p. 100231
• Main Authors: Li, Mengya, Yu, Guanghui, Cao, Congli, Liu, Pei
• Format: Journal Article
• Language: English
• Published: China Elsevier Inc 13.09.2021; Elsevier
• Subjects: Biological Transport; cellular compartmentation; Cyclopentanes - metabolism; jasmonates; metabolism; Oxylipins - metabolism; Plant Growth Regulators - metabolism; Plant Physiological Phenomena; Plants - metabolism; Review; Signal Transduction; signaling; transport; jasmonates; metabolism; signaling; transport; cellular compartmentation
• ISSN: 2590-3462; 2590-3462
• DOI: 10.1016/j.xplc.2021.100231

Biosynthesis/metabolism, perception/signaling, and transport are three essential aspects of the actions of phytohormones. Jasmonates (JAs), including jasmonic acid (JA) and related oxylipins, are implicated in the regulation of a range of ecological interactions, as well as developmental programs to integrate these interactions. Jasmonoyl-isoleucine (JA-Ile) is the most bioactive JAs, and perception of JA-Ile by its coreceptor, the Skp1-Cullin1-F-box-type (SCF) protein ubiquitin ligase complex SCFCOI1-JAZ, in the nucleus derepresses the transcriptional repression of target genes. The biosynthesis and metabolism of JAs occur in the plastid, peroxisome, cytosol, endoplasmic reticulum, and vacuole, whereas sensing of JA-Ile levels occurs in the nucleus. It is increasingly apparent that a number of transporters, particularly members of the jasmonates transporter (JAT) family, located at endomembranes as well as the plasma membrane, constitute a network for modulating and coordinating the metabolic flux and signaling of JAs. In this review, we discuss recent advances in the metabolism, signaling, and especially the transport of JAs, focusing on intracellular compartmentation of these processes. The roles of transporter-mediated cell-cell transport in driving long-distance transport and signaling of JAs are also discussed. The complex intracellular compartmentation of JA synthesis, metabolism, and signaling provides a new regulatory layer for coordinating JA metabolic flux and signaling dynamics. A number of transporters located at endomembranes and the plasma membrane constitute a network that facilitates the transport of JAs. Here, the metabolism, signaling, and transport of JAs are reviewed through the lens of their intra- and intercellular distributions.