Glucocorticoid receptor mediated the propofol self-administration by dopamine D1 receptor in nucleus accumbens

• Published in: Neuroscience Vol. 328; pp. 184 - 193
• Main Authors: Wu, Binbin, Liang, Yuyuan, Dong, Zhanglei, Chen, Zhichuan, Zhang, Gaolong, Lin, Wenxuan, Wang, Sicong, Wang, Benfu, Ge, Ren-Shan, Lian, Qingquan
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 22.07.2016
• Subjects: Aldosterone - pharmacology; Animals; corticosterone; Corticosterone - blood; D1 receptor; dexamethasone; Dexamethasone - pharmacology; Disease Models, Animal; Dose-Response Relationship, Drug; Glucocorticoids - pharmacology; Hormone Antagonists - pharmacology; Hypnotics and Sedatives - administration & dosage; Male; Mifepristone - pharmacology; Mineralocorticoid Receptor Antagonists - pharmacology; Motor Activity - drug effects; Neurology; Nucleus Accumbens - drug effects; Nucleus Accumbens - metabolism; propofol; Propofol - administration & dosage; Rats, Sprague-Dawley; Receptors, Dopamine D1 - metabolism; Receptors, Glucocorticoid - agonists; Receptors, Glucocorticoid - antagonists & inhibitors; Receptors, Glucocorticoid - metabolism; Receptors, Mineralocorticoid - agonists; Receptors, Mineralocorticoid - metabolism; Self Administration; Substance-Related Disorders - drug therapy; Substance-Related Disorders - metabolism; VTA; propofol; hypothalamic–pituitary–adrenal axis; NAc; analysis of variance; dopamine D2 receptor; ANOVA; D2 receptor; glucocorticoid receptors; glucocorticoids; GC; dexamethasone; D1 receptor; FR1; MR; GR; mineralocorticoid receptor; nucleus accumbens; fixed ratio 1; ventral tegmental area; self-administration; enzyme-linked immunosorbent assay; HPA; corticosterone; dopamine D1 receptor; ELISA
• ISSN: 0306-4522; 1873-7544
• DOI: 10.1016/j.neuroscience.2016.04.029

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