Recent advances in photoredox and nickel dual-catalyzed cascade reactions: pushing the boundaries of complexity

Cascade reactions that produce multiple chemical bonds in one synthetic operation are important in the efficient construction of complex molecules. In addition, photoredox and nickel dual catalysis opens a new and powerful avenue for transition-metal-catalyzed cross-coupling reactions. By combining...

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Published inChemical science (Cambridge) Vol. 11; no. 16; pp. 451 - 464
Main Authors Zhu, Chen, Yue, Huifeng, Chu, Lingling, Rueping, Magnus
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 28.04.2020
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Summary:Cascade reactions that produce multiple chemical bonds in one synthetic operation are important in the efficient construction of complex molecules. In addition, photoredox and nickel dual catalysis opens a new and powerful avenue for transition-metal-catalyzed cross-coupling reactions. By combining these two concepts, photoredox and nickel dual-catalyzed cascade reactions have been recently established, and they provide an efficient and mild method for accessing a series of valuable organic compounds. Cascade reactions that produce multiple chemical bonds in one synthetic operation are important in the efficient construction of complex molecules.
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These authors contributed equally to this work.
ISSN:2041-6520
2041-6539
DOI:10.1039/d0sc00712a