Circulating microRNA profiling in patients with advanced non-squamous NSCLC receiving bevacizumab/erlotinib followed by platinum-based chemotherapy at progression (SAKK 19/05)
Highlights • We performed extensive micro-RNA profiling in 50 patients with advanced NSCLC. • Patients received erlotinib/bevacizumab followed by chemotherapy at progression. • Micro-RNA profiling was performed in peripheral blood samples at start of treatment. • Six micro-RNA's were significan...
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Published in | Lung cancer (Amsterdam, Netherlands) Vol. 85; no. 2; pp. 306 - 313 |
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Main Authors | , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford
Elsevier Ireland Ltd
01.08.2014
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | Highlights • We performed extensive micro-RNA profiling in 50 patients with advanced NSCLC. • Patients received erlotinib/bevacizumab followed by chemotherapy at progression. • Micro-RNA profiling was performed in peripheral blood samples at start of treatment. • Six micro-RNA's were significantly and independently associated with survival. • High expression of micro-RNA 29a was associated with a markedly decreased survival. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0169-5002 1872-8332 |
DOI: | 10.1016/j.lungcan.2014.04.014 |