Endophthalmitis post pars plana vitrectomy surgery: incidence, organisms' profile, and management outcome in a tertiary eye hospital in Saudi Arabia

• Published in: Middle East African journal of ophthalmology Vol. 28; no. 1; pp. 1 - 5
• Main Authors: AlBloushi, Bedoor, Mura, Marco, Khandekar, Rajiv, AlMesfer, Saleh, AlYahya, Abdulmalik, Alabduljabbar, Khaled, AlRefaie, Shaimaa, Semidey, Valmore
• Format: Journal Article
• Language: English
• Published: Riyadh Wolters Kluwer India Pvt. Ltd 01.01.2021; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow
• Subjects: Endophthalmitis; Eye surgery; Medical records; Medical research; Medicine, Experimental; Ophthalmology; Original; Pay-per-view television; Surgery; Surgical outcomes; Middle East; pars plana vitrectomy; Endophthalmitis; intraocular infection
• ISSN: 0974-9233; 0975-1599; 0975-1599; 0974-9233
• DOI: 10.4103/meajo.MEAJO_424_20

PURPOSE: To determine the incidence of endophthalmitis after pars plana vitrectomy (PPV), organisms' profile, and management outcomes at a tertiary eye hospital in a Middle East country. METHODS: In this single-arm cohort study conducted in 2020, medical records of patients who underwent PPV not accompanied by any other intraocular surgery were reviewed; those with a diagnosis of acute endophthalmitis in the immediate postoperative period (within 6 weeks) during the past 6 years were analyzed. RESULTS: A total of 8153 records of PPV surgeries were reviewed. Five cases had endophthalmitis post-PPV with an incidence of 0.061%. Three (0.037%) had positive cultures, all of them for Staphylococcus epidermidis. The interval between PPV and diagnosis of endophthalmitis ranged from 3 to 25 days (mean, 15.8 days). Final vision after treatment ranged from 20/400 to no light perception, and one eye was eviscerated. CONCLUSION: The incidence of endophthalmitis post PPV is low. Despite prompt diagnosis and standard management, visual prognosis seems to be poor. The infective agents for endophthalmitis were commensals from the ocular surface.