Neuroendocrine effects of a single bout of functional and core stabilization training in women with chronic nonspecific low back pain: A crossover study

• Published in: Physiological reports Vol. 10; no. 17; pp. e15365 - n/a
• Main Authors: Santos, Marta Silva, Santos, Poliana de Jesus, Vasconcelos, Alan Bruno Silva, Gomes, Ana Carolina Amado, Oliveira, Luciana Maria, Souza, Patrícia Rodrigues Marques, Heredia‐Elvar, Juan Ramón, Da Silva‐Grigoletto, Marzo Edir
• Format: Journal Article
• Language: English
• Published: Oxford John Wiley & Sons, Inc 01.09.2022; John Wiley and Sons Inc; Wiley
• Subjects: activities of daily living; analgesia; Analgesics; Back pain; Endorphins; Estrogens; Exercise; Low back pain; Manipulative therapy; Motor task performance; Neuroendocrine system; opioid peptides; Original; pain; Physical fitness; Plasma; spine; Volunteers
• ISSN: 2051-817X
• DOI: 10.14814/phy2.15365

Exercise‐induced hypoalgesia (EIH) is characterized as the pain reduction after an exercise session and it seems to be related to the release of plasma β‐endorphin. In this sense, the core stabilization training (CT) has been suggested for patients with chronic nonspecific low back pain (CNSLBP), but it is unclear whether it induces EIH. Patients with CNSLBP have neuromotor dysfunctions that can affect the performance of functional tasks, thus, performing functional training (FT) could improve motor control and promote EIH, since functional training uses multi‐joint exercises that aim to improve the functionality of actions performed in daily life. EIH is usually assessed using quantitative sensory tests (QST) such as conditioned pain modulation, pressure pain threshold, and temporal summation. Thus, the sum of parameters from quantitative sensory tests and plasma β‐endorphin would make it possible to understand what the neuroendocrine effects of FT and CT session are. Our study compared the acute effect of CT and FT on the EIH and plasma β‐endorphin release, and correlated plasma β‐endorphin with quantitative sensory testing in patients with CNSLBP. Eighteen women performed two training sessions (CT and FT) with an interval of 48 h between sessions. EIH was assessed by QST and plasma β‐endorphin levels. Results showed that only FT significantly increased plasma β‐endorphin (FT p < 0.01; CT p = 0.45), which correlated with pain pressure threshold (PPT) and conditioned pain modulation (CPM). However, QST values were not different in women with CNSLBP after CT or FT protocols. Plasma β‐endorphin correlated with PPT and CPM, however, the same did not occur with a temporal summation. Women are more affected by chronic nonspecific low back pain; Women submitted to a single bout of functional training have increased plasma beta‐endorphin concentrations; Although it has increased plasma beta‐endorphin, a single bout of functional training did not cause exercise‐induced hypoalgesia.