Hyperthermia for locally advanced breast cancer

Hyperthermia (HT) has a proven benefit for treating superficial malignancies, particularly chest wall recurrences of breast cancer. There has been less research utilising HT in patients with locally advanced breast cancer (LABC), but available data are promising. HT has been combined with chemothera...

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Published inInternational journal of hyperthermia Vol. 26; no. 7; pp. 618 - 624
Main Authors Zagar, Timothy M., Oleson, James R., Vujaskovic, Zeljko, Dewhirst, Mark W., Craciunescu, Oana I., Blackwell, Kimberly L., Prosnitz, Leonard R., Jones, Ellen L.
Format Journal Article
LanguageEnglish
Published England Informa UK, Ltd 01.10.2010
Taylor & Francis
Subjects
Breast Neoplasms - drug therapy
Breast Neoplasms - radiotherapy
Breast Neoplasms - therapy
Combined Modality Therapy
Female
Humans
hyperthermia
Hyperthermia, Induced
locally advanced breast cancer
radiation
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Summary:Hyperthermia (HT) has a proven benefit for treating superficial malignancies, particularly chest wall recurrences of breast cancer. There has been less research utilising HT in patients with locally advanced breast cancer (LABC), but available data are promising. HT has been combined with chemotherapy and/or radiotherapy in the neoadjuvant, definitive and adjuvant setting, albeit in series with small numbers of patients. There is only one phase III trial that examines hyperthermia in LABC, also with relatively small numbers of patients. The goal of this review is to highlight important research utilising HT in patients with LABC as well as to suggest future directions for its use.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0265-6736
1464-5157
DOI:10.3109/02656736.2010.501051