High Prevalence of Respiratory Viral Infections in Patients Hospitalized in an Intensive Care Unit for Acute Respiratory Infections as Detected by Nucleic Acid-Based Assays

Forty-seven bronchoalveolar lavages (BAL) were obtained from 41 patients with acute pneumonia attending an intensive care unit. By molecular diagnosis, 30% of total BAL and 63% of bacteria-negative BAL were positive for respiratory viruses. Molecular detection allows for high-rate detection of respi...

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Published inJournal of Clinical Microbiology Vol. 43; no. 1; pp. 455 - 457
Main Authors Legoff, Jérôme, Guérot, Emmanuel, Ndjoyi-Mbiguino, Angélique, Matta, Mathieu, Si-Mohamed, Ali, Gutmann, Laurent, Fagon, Jean-Yves, Bélec, Laurent
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 2005
Subjects
Acute Disease
Biological and medical sciences
Bronchoalveolar Lavage Fluid - virology
DNA, Viral - analysis
DNA, Viral - isolation & purification
Female
Fundamental and applied biological sciences. Psychology
Hospitalization
Humans
Infectious diseases
Intensive Care Units
Male
Medical sciences
Microbiology
Middle Aged
Polymerase Chain Reaction - methods
Prevalence
Respiratory Tract Infections - epidemiology
Respiratory Tract Infections - virology
Reverse Transcriptase Polymerase Chain Reaction - methods
RNA, Viral - analysis
RNA, Viral - isolation & purification
Virology
Virus Diseases - epidemiology
Virus Diseases - virology
Viruses - genetics
Viruses - isolation & purification
Infection
Human
Prevalence
Microbiology
Acute
Viral disease
Detection
Epidemiology
Nucleic acid
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Summary:Forty-seven bronchoalveolar lavages (BAL) were obtained from 41 patients with acute pneumonia attending an intensive care unit. By molecular diagnosis, 30% of total BAL and 63% of bacteria-negative BAL were positive for respiratory viruses. Molecular detection allows for high-rate detection of respiratory viral infections in adult patients suffering from severe pneumonia.
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Corresponding author. Mailing address: Laboratoire de Microbiologie, Hôpital Européen Georges Pompidou, 20 Rue Leblanc, 75908 Paris Cedex 15, France. Phone: 331 56 09 39 58. Fax: 331 56 09 24 47. E-mail: jerome.le-goff@egp.ap-hop-paris.fr.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.43.1.455-457.2005