Frequency and risk factors of H. pylori infection among dental students: an observational cross-sectional study
Despite Helicobacter pylori infection remains asymptomatic in most people, it is associated with an increased risk of gastric cancer. Considering Egypt had the highest prevalence of H. pylori in healthy asymptomatic population in adults and pediatric age in past studies and currently salivary ELISA...
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Published in | Scientific reports Vol. 13; no. 1; p. 14264 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
London
Nature Publishing Group UK
31.08.2023
Nature Publishing Group Nature Portfolio |
Subjects | |
Online Access | Get full text |
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Summary: | Despite
Helicobacter pylori
infection remains asymptomatic in most people, it is associated with an increased risk of gastric cancer. Considering Egypt had the highest prevalence of
H. pylori
in healthy asymptomatic population in adults and pediatric age in past studies and currently salivary ELISA could be used for diagnosis of Oral
H. pylori
infection. Moreover, some researchers speculated that dentists and dental students might be at a higher risk for oral
H. pylori
infection because they are the most frequently exposed ones to saliva and dental plaqu
e.
This study aimed to determine risk factors associated with frequency of
H. pylori
among a sample of dental students for better management of the disease. 83 participants, with age (21–25 years), attending Faculty of Dentistry, Fayoum University were recruited. A structured questionnaire was used to collect information on sociodemographic parameters and risk factors for
H. pylori
. Direct inquiry about dyspeptic symptoms were done. Saliva samples were collected and tested for H. pylori antibodies. Overall seroprevalence was 22.9%. Participants in internship were more prone to be positive (
p
= 0.005). 32.6% of urban residents versus 10.8% of rural were
H. pylori
positive (
p
= 0.019). 75.0% of previous history of
H. pylori
infection versus 14.1% of those with no history were
H. pylori
positive
p
< 0.001. 70% of positive
H. pylori
participants reported positive clinical symptoms that were statistically significant. This study suggests that middle income, previous history of
H. pylori
and clinical symptoms of dyspepsia are risk factors of oral
H. pylori
with a decline in its prevalence in Egypt. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3 |
ISSN: | 2045-2322 2045-2322 |
DOI: | 10.1038/s41598-023-41246-7 |