Off-wafer fabrication and surface modification of asymmetric 3D SU-8 microparticles

This protocol details a method of fabricating off-wafer, multilayered, asymmetric microparticles from the epoxy-based photosensitive polymer SU-8. Also included are methods for altering the surface properties of SU-8 and introducing functional groups for further covalent coupling reactions. These te...

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Bibliographic Details
Published inNature protocols Vol. 1; no. 6; pp. 3153 - 3158
Main Authors Desai, Tejal A, Tao, Sarah L, Popat, Ketul
Format Journal Article
LanguageEnglish
Published England Nature Publishing Group 01.01.2007
Subjects
Biomedical materials
Chemical synthesis
Design
Drug delivery systems
Epoxy Compounds - chemistry
Humidity
Methods
Microspheres
Polymers - chemistry
Production processes
Properties
Protocol
Silicon wafers
Software
Sulfuric acid
Surface chemistry
Surface Properties
Tissue engineering
Topography
United States
United States > US
San Francisco California
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Summary:This protocol details a method of fabricating off-wafer, multilayered, asymmetric microparticles from the epoxy-based photosensitive polymer SU-8. Also included are methods for altering the surface properties of SU-8 and introducing functional groups for further covalent coupling reactions. These techniques may be used to create microparticles for applications in drug delivery and tissue engineering. Microparticle design, fabrication and surface modification can be completed in 2 d.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1754-2189
1750-2799
DOI:10.1038/nprot.2006.451