Understanding the molecular basis of disease is crucial to improving the design and construction of herpesviral vectors for veterinary vaccines

• Published in: Vaccine Vol. 33; no. 44; pp. 5897 - 5904
• Main Author: Mahony, T.J
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 04.11.2015; Elsevier Limited
• Subjects: Allergy and Immunology; Animal production; Animals; Antigens; Bovine herpesvirus 1; Bovine respiratory disease; Cattle; Chickens; Disease; Drug Discovery - methods; Drug resistance; Gallid herpesvirus 2; Genetic engineering; Genomes; Herpesviridae - genetics; Herpesviridae - immunology; Herpesviridae - pathogenicity; Herpesvirus Vaccines - genetics; Herpesvirus Vaccines - immunology; Herpesvirus Vaccines - isolation & purification; Infections; Infectious Bovine Rhinotracheitis - prevention & control; Infectious Bovine Rhinotracheitis - virology; Laboratories; Livestock; Marek Disease - prevention & control; Marek Disease - virology; Marek's disease; Meleagrid herpesvirus 1; Pathogens; Respiratory diseases; Studies; Vaccines; Vectors (Biology); Veterinary Medicine - methods; Veterinary vaccine; Viral infections; Viruses; Gallid herpesvirus 2; Veterinary vaccine; Bovine herpesvirus 1; Meleagrid herpesvirus 1; Marek's disease; Bovine respiratory disease
• ISSN: 0264-410X; 1873-2518
• DOI: 10.1016/j.vaccine.2015.09.028

Highlights • Review of viral vectors used to control veterinary diseases. • Focus on herpesviruses as causative agents and vaccine vectors. • Discussed in the context of Marek's disease and bovine respiratory disease. • Identification the knowledge gaps to be addressed to improve disease control. • Identification of key technologies to drive development of better vaccines.