Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma

Cholangiocarcinoma (CCA) is an adenocarcinoma originating from the epithelial cells of the bile ducts/hepatocytes or peribiliary glands. There are three types of cholangiocarcinoma: intrahepatic, perihilar and distal. CCA represents approximately 3% of the gastrointestinal malignancies. The incidenc...

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Published inDiagnostics (Basel) Vol. 14; no. 5; p. 490
Main Authors Caragut, Roxana-Luiza, Ilie, Madalina, Cabel, Teodor, Günșahin, Deniz, Panaitescu, Afrodita, Pavel, Christopher, Plotogea, Oana Mihaela, Rînja, Ecaterina Mihaela, Constantinescu, Gabriel, Sandru, Vasile
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 24.02.2024
MDPI
Subjects
Abdomen
Antigens
Bile ducts
biliary drainage
Biomarkers
Care and treatment
Cholangiocarcinoma
Cholangitis
Comparative analysis
diagnosis
digestive oncology
endoscopic retrograde cholangiopancreatography
Endoscopy
Hepatitis B
Hypercalcemia
Infections
Inflammation
Liver
Liver cancer
Liver cirrhosis
Mutation
Parasites
Phosphatase
Review
Risk factors
Tomography
Type 2 diabetes
Ultrasonic imaging
endoscopic retrograde cholangiopancreatography
diagnosis
endoscopy
digestive oncology
cholangiocarcinoma
endoscopic ultrasound
biliary drainage
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Summary:Cholangiocarcinoma (CCA) is an adenocarcinoma originating from the epithelial cells of the bile ducts/hepatocytes or peribiliary glands. There are three types of cholangiocarcinoma: intrahepatic, perihilar and distal. CCA represents approximately 3% of the gastrointestinal malignancies. The incidence of CCA is higher in regions of the Eastern world compared to the Western countries. There are multiple risk factors associated with cholangiocarcinoma such as liver fluke, primary sclerosing cholangitis, chronic hepatitis B, liver cirrhosis and non-alcoholic fatty liver disease. Endoscopy plays an important role in the diagnosis and management of cholangiocarcinoma. The main endoscopic methods used for diagnosis, biliary drainage and delivering intrabiliary local therapies are endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. The purpose of this review is to analyze the current data found in literature about cholangiocarcinoma, with a focus on the actual diagnostic tools and endoscopic management options.
Bibliography:ObjectType-Article-2
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ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics14050490