Recent Developments in Polymer Nanocomposites for Bone Regeneration

• Published in: International journal of molecular sciences Vol. 24; no. 4; p. 3312
• Main Authors: Abbas, Mohamed, Alqahtani, Mohammed S, Alhifzi, Roaa
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 07.02.2023; MDPI
• Subjects: Biocompatibility; Biological activity; Biological products; biomaterials; Biomedical materials; Bone biomaterials; Bone growth; Bone healing; bone regeneration; Bones; Carbon; ceramic matrix composites; Cerium oxides; Cytotoxicity; Embryogenesis; Fractures; Free radicals; Graphene; Hydrogels; Hydroxyapatite; Immune system; Mineralization; Nanocomposites; Nanomaterials; Nanoparticles; Osteogenesis; Phosphatase; Physiological aspects; Polymer matrix composites; Polymers; Regeneration; Regeneration (physiology); Review; scaffolds; Stem cells; Tissue engineering; Transplants & implants; Wound healing; United Kingdom; Netherlands; bone regeneration; scaffolds; biomaterials; ceramic matrix composites; nanocomposites
• ISSN: 1422-0067; 1661-6596; 1422-0067
• DOI: 10.3390/ijms24043312

Most people who suffer acute injuries in accidents have fractured bones. Many of the basic processes that take place during embryonic skeletal development are replicated throughout the regeneration process that occurs during this time. Bruises and bone fractures, for example, serve as excellent examples. It almost always results in a successful recovery and restoration of the structural integrity and strength of the broken bone. After a fracture, the body begins to regenerate bone. Bone formation is a complex physiological process that requires meticulous planning and execution. A normal healing procedure for a fracture might reveal how the bone is constantly rebuilding as an adult. Bone regeneration is becoming more dependent on polymer nanocomposites, which are composites made up of a polymer matrix and a nanomaterial. This study will review polymer nanocomposites that are employed in bone regeneration to stimulate bone regeneration. As a result, we will introduce the role of bone regeneration nanocomposite scaffolds, and the nanocomposite ceramics and biomaterials that play a role in bone regeneration. Aside from that, recent advances in polymer nanocomposites might be used in a variety of industrial processes to help people with bone defects overcome their challenges will be discussed.