Allele frequencies of 23 autosomal short tandem repeat loci in the Philippine population

• Published in: Legal medicine (Tokyo, Japan) Vol. 17; no. 4; pp. 295 - 297
• Main Authors: Rodriguez, Jae Joseph Russell Beltran, Salvador, Jazelyn M, Calacal, Gayvelline C, Laude, Rita P, De Ungria, Maria Corazon A
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01.07.2015
• Subjects: Allele frequency; Asian Continental Ancestry Group - ethnology; Asian Continental Ancestry Group - genetics; DNA Fingerprinting - methods; Forensic Genetics - methods; Gene Frequency; Genetic Loci; Genetic Variation; Genetics, Population; Humans; Internal Medicine; Male; Microsatellite Repeats - genetics; Philippines; Polymerase Chain Reaction; Population database; PowerPlex® 21 system; Short tandem repeat; Verifiler™ direct PCR amplification kit; Philippines; PowerPlex® 21 system; Allele frequency; Verifiler™ direct PCR amplification kit; Short tandem repeat; Philippines; Population database
• ISSN: 1344-6223; 1873-4162
• DOI: 10.1016/j.legalmed.2015.02.005

Abstract We characterized diversity and forensic descriptive parameters of 23 autosomal STR loci (CSF1PO, D13S317, D16S539, D5S818, D7S820, TPOX, D18S51, D21S11, D3S1358, D8S1179, FGA, TH01, vWA, D1S1656, D10S1248, D12S391, D2S441, D22S1045, D19S433, D2S1338, D6S1043, Penta D and Penta E) among 167 unrelated Filipinos. The most variable autosomal STR loci observed is Penta E (observed heterozygosity: 0.9222, match probability: 0.0167). Results reveal matching probability of 8.21 × 10−28 for 23 autosomal STR loci. This dataset for the Philippine population may now be used in evaluating the weight of DNA evidence for forensic applications such as in human identification, parentage/kinship testing, and interpretation of DNA mixtures.