Orthostatic blood pressure changes and diabetes duration

• Published in: Journal of diabetes and its complications Vol. 36; no. 5; p. 108169
• Main Authors: Idiaquez Rios, Juan F., Lovblom, Leif Erik, Perkins, Bruce A., Bril, Vera
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2022; Elsevier Limited
• Subjects: Age; Blood pressure; Cardiovascular disease; Diabetes; Diabetic autonomic neuropathy; Diabetic neuropathy; Glucose; Hypertension; Measurement techniques; Mortality; Orthostatic hypotension; Patients; Variance analysis; Hypertension; Diabetic neuropathy; Diabetic autonomic neuropathy; Orthostatic hypotension
• ISSN: 1056-8727; 1873-460X; 1873-460X
• DOI: 10.1016/j.jdiacomp.2022.108169

To determine the prevalence and the associated clinical characteristics of orthostatic hypotension and orthostatic hypertension in patients with diabetic sensorimotor polyneuropathy (DSP). A single-center retrospective cross-sectional study was conducted on 200 DSP patients who had 3-minute orthostatic measures as part of the standard clinic evaluation. We measured the heart rate (HR) and blood pressure (BP) supine and again after 3 min of standing. The prevalence of orthostatic hypotension was 19.5% and that of orthostatic hypertension was 23%. Subjects with orthostatic hypotension had significantly longer diabetes duration than subjects who were normotensive and those with orthostatic hypertension. Quantitatively, BP changes from supine to standing correlated with diabetes duration (R = 0.306; P = 0.0582) and age (R = 0.434; P = 0.006) in subjects with orthostatic hypotension. Orthostatic hypertension and orthostatic hypotension are frequent in patients with DSP. Orthostatic hypertension is associated with shorter diabetes duration than orthostatic hypotension. •Orthostatic hypertension and orthostatic hypotension are frequent in DSP.•BP changes from supine to standing correlated positively with diabetes duration.•Supine and 3 min standing BP is a simple bedside test for orthostatic hypertension and orthostatic hypotension in DSP.