Draft genome sequence data of Streptomyces sp. SS1-1, an endophytic strain showing cytotoxicity against the human lung cancer A549 cell line

• Published in: Data in brief Vol. 30; p. 105497
• Main Authors: Nguyen, Quan Dang, Truong, Phung Minh, Vo, Thao Nguyen Thanh, Chu, Truc Dao Xuan, Nguyen, Chuong Hoang
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.06.2020; Elsevier
• Subjects: A549 cell line; Cytotoxicity; Genetics, Genomics and Molecular Biology; NGS; SS1-1; Streptomyces; Streptomyces; Cytotoxicity; NGS; A549 cell line; SS1-1
• ISSN: 2352-3409; 2352-3409
• DOI: 10.1016/j.dib.2020.105497

We report in this article the cytotoxicity of Streptomyces sp. SS1-1 against the human lung cancer A549 cell line, its draft genome sequence and a total of 20 predicted secondary metabolite biosynthetic gene clusters. Streptomyces sp. SS1-1 was an endophytic bacterial strain isolated from the plant Catharanthus roseus in Ho Chi Minh City, Vietnam. When cultured in the PY medium, this strain shows a cytotoxic effect on the A549 cell line. The draft genome of Streptomyces sp. SS1-1 has four contigs of total 7,815,656 bp and the GC content of this genome is 72.2%. AntiSMASH analysis reveals 20 putative biosynthetic gene clusters for the largest contig. The genome sequencing of Streptomyces sp. SS1-1 is essential for the molecular identification of gene cluster(s) responsible for secondary metabolite(s) with cytotoxic activity.