Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA

• Published in: Data in brief Vol. 18; pp. 1433 - 1440
• Main Authors: Hirsch, Mauro Mozael, Deckmann, Iohanna, Fontes-Dutra, Mellanie, Bauer-Negrini, Guilherme, Nunes, Gustavo Della-Flora, Nunes, Walquiria, Rabelo, Bruna, Riesgo, Rudimar, Margis, Rogerio, Bambini-Junior, Victorio, Gottfried, Carmem
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.06.2018; Elsevier
• Subjects: Autism; microRNA; Pharmacology, Toxicology and Pharmaceutical Science; Preclinical models; Resveratrol; Social transmission of food preference; Translational research; Valproate; Autism; Translational research; Social transmission of food preference; Resveratrol; microRNA; Preclinical models; Valproate
• ISSN: 2352-3409; 2352-3409
• DOI: 10.1016/j.dib.2018.04.047

This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavored food by male rats prenatally exposed to valproic acid (VPA) and treated with resveratrol (RSV), showed that VPA animals show a trend to eat less of the flavored food presented by a demonstrator rat. We also identified 13 microRNA with similar levels among rodents’ experimental groups, as well as 11 microRNA with no alterations between autistic and control subjects. Further evaluation of mechanisms of VPA and RSV actions on behavioral and molecular alterations can shed light in important biomarkers and etiological triggers of autistic spectrum disorders.