Identification of pyroptosis related subtypes and tumor microenvironment infiltration characteristics in breast cancer

• Published in: Scientific reports Vol. 12; no. 1; pp. 10640 - 15
• Main Authors: Huang, Guo, Zhou, Jun, Chen, Juan, Liu, Guowen
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 23.06.2022; Nature Publishing Group; Nature Portfolio
• Subjects: 631/250; 631/67/1347; 692/4028; 692/499; Breast cancer; Humanities and Social Sciences; Immunosuppressive agents; Immunotherapy; Infiltration; Medical prognosis; Metastases; multidisciplinary; Mutation; p53 Protein; Patients; Prognosis; Pyroptosis; Science; Science (multidisciplinary); Tumor microenvironment; Tumors

Understanding the association of pyroptosis with tumor progression, prognosis and effect on immunotherapeutic response in breast cancer (BC) is limited. This study analysed forty pyroptosis-related genes to construct the pyroptosis score. Association of the pyroptosis score with the overall survival...