Physiological responses and adaptations to high methane production in Japanese Black cattle

• Published in: Scientific reports Vol. 12; no. 1; p. 11154
• Main Authors: Kim, Minji, Masaki, Tatsunori, Ikuta, Kentaro, Iwamoto, Eiji, Nishihara, Koki, Hirai, Makoto, Uemoto, Yoshinobu, Terada, Fuminori, Roh, Sanggun
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.07.2022; Nature Publishing Group; Nature Portfolio
• Subjects: 631/443/319/320; 631/601/1737; Adaptation; Amino acids; Blood; Cattle; Efficiency; Emission measurements; Emissions; Energy; Feeds; Fermentation; Glucose; Glucose metabolism; Glucose transport; Hormones; Humanities and Social Sciences; Insulin; Insulin-like growth factors; Liver; Livestock; Metabolism; Metabolites; Methane; Methanogenesis; Microorganisms; multidisciplinary; Phosphatase; Physiological responses; Physiology; Production increases; Propionic acid; Science; Science (multidisciplinary); Transcriptomes
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-022-15146-1

In this study, using enteric methane emissions, we investigated the metabolic characteristics of Japanese Black cattle. Their methane emissions were measured at early (age 13 months), middle (20 months), and late fattening phases (28 months). Cattle with the highest and lowest methane emissions were selected based on the residual methane emission values, and their liver transcriptome, blood metabolites, hormones, and rumen fermentation characteristics were analyzed. Blood β-hydroxybutyric acid and insulin levels were high, whereas blood amino acid levels were low in cattle with high methane emissions. Further, propionate and butyrate levels differed depending on the enteric methane emissions. Hepatic genes, such as SERPINI2, SLC7A5, ATP6 , and RRAD , which were related to amino acid transport and glucose metabolism, were upregulated or downregulated during the late fattening phase. The above mentioned metabolites and liver transcriptomes could be used to evaluate enteric methanogenesis in Japanese Black cattle.